Directory Forum Gallery Facts & Trivia Genetics History Linguistics Friends Finder Europe Guide Belgium England France Germany Italy Netherlands Scotland Wales Eupedia Top > Europe Guide Top > Genetics > Mutations related to cardiovascular problems Genetically inherited traits, conditions and diseases What can DNA tell you about yourself ? Cardiovascular diseases Autoimmune diseases Other diseases Cancers Neuro-psychological conditions Physical & health-related traits List of cardiovascular diseases with the associated genes => 10 conditions and 105 SNP's listed. Risk alleles : Substantially lower risk (over 3x less), moderately lower risk (up to 3x less), normal, slightly higher risk (up to 3x more), greatly increased risk (over 3x more). Normal alleles marked with a * mean that the person is a carrier of the disease. Depending on the testing company, sometimes A is reported as T, and G is reported as C, or vice-versa.Question marks (?) mean that we doubt the validity of the risk alleles because of their very high frequency. Testing companies : 1 = 23andMe ; 2 = DeCODEme Bold numbers indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme. However, as deCODEme tests almost twice more SNP's than 23andMe, most of the SNP's tested by 23andMe are also tested by deCODEme. Description Chromosome Gene SNP Risk alleles Tested by* Links   Abdominal Aortic Aneurysm 5 MTRR rs326118   7 IL6 rs1800796 CC, CG, GG 1     9 intergenic rs10116277 GG, GT, TT 1, 2   9 intergenic rs10757278 AA, AG, GG 1     9 intergenic rs10811661 1     14 MTHFD1 rs8003379 1 Intracranial Aneurysm 1 1p34-36   2 BOLL rs700651 AA, AG, GG 1   5 CSPG2 rs173686 CC, CT, TT 1     7 7q11   8 intergenic rs10958409 AA, AG, GG 1     9 intergenic rs10757278 AA, AG, GG 1     9 intergenic rs1333040 CC, CT, TT 1     9 9p21 rs10116277 1, 2     11 11q25   14 14q23–q31 rs767603 CC, CT, TT     19 19q13.1-13.3 Atherosclerosis (hyperlipidemia) 1 USF1 rs2516839 CC, CT, TT 1         rs2073658 CC, CT, TT 1     4 FGB rs1800787 CC, CT, TT 1   Atrial Fibrillation 1 EDN2 rs5800 AA, AG, GG   4 AF (4q25) rs10033464 GG, GT, TT 1, 2   rs2200733 CC, CT, TT 1, 2 6 6q14-16 region 10 10q22 region Cardiovascular disease 1 FMN2 rs17672135 CC, CT, TT 1 SNPedia   1 PSRC1 rs599839 AA, AG, GG 1, 2 ?   1 CRP rs3091244     2 HSPD1 rs788016 AA, AG, GG 1 ?       rs2565163 AA, AG, GG   ?       rs2340690 CC, CT, TT     2 HSPE1 rs2305560 CC, CT, TT       5 intergenic rs383830 AA, AT, TT 1     6 MTHFD1L rs6922269 AA, AG, GG 1     7 NOS3 rs1799983 GG, GT, TT 1         rs207044 CC, CT, TT         rs1800779 AA, AG, GG 1         rs1800783 AA, AT, TT     9 intergenic rs10757274 AA, AG, GG 1 ?   9 intergenic rs2383206 AA, AG, GG 1 ?   10 intergenic rs501120 AA, AG, GG 1 ?   11 MMP3 rs3025058 DD, DI, II 1 ?   11 MYBPC3     13 KL rs9536314 GG, GT, TT 1 ?       rs9527025 CC, CG, GG     15 SMAD3 rs17228212 CC, CT, TT 1     16 CDH13 rs8055236 GG, GT, TT 1     17 ACE rs1799752 DD, DI, II 1 Link   19 intergenic rs7250581 AA, AG, GG 1     22 SEZ6L rs688034 CC, CT, TT 1   Cardiovascular disease (early onset) 3 GATA2 rs2713604 CC, CT, TT 1         rs3803 AA, AG, GG 1   Cardiovascular disease (cholesterol level) 1 CELSR2 rs4970834 1     1 ARHGAP30 rs2774279 CC, CT, TT 1     2 intergenic rs2943634 AA, AC, CC 1     6 EDN1 rs5370 GG, GT, TT 1     8 LPL rs326 AA, AG, GG 1   15 LIPC rs1800588 CC, CT, TT 1     16 CETP rs183130 CC, CT, TT 1     18 MC4R rs2229616 AA, AG, GG 1     20 PLTP rs3843763 CC, CT, TT 1   Myocardial infarction (heart attack) 1 PSRC1 rs599839 AA, AG, GG 1, 2 ?   1 TNFSF4 rs1234315 CC, CT, TT 1 ?     rs1234312       rs1234313 AA, AG, GG 1 ?     rs3850641 AA, AG, GG 1       rs3861950     3 ITIH3         5 IL4 rs2243250 CC, CT, TT 1     9 9p21 rs10116277 GG, GT, TT 1, 2 Link   9 9p21 rs2383207 AA, AG, GG 1       rs1537375 CC, CT, TT 1     9 9p21 rs10757278 AA, AG, GG 1     9 9p21 rs1333049 CC, CG, GG 1   9 TLR4 rs4986790 AA, AG, GG 1     11 MMP3 rs3025058 DD, DI, II 1 ?   12 SH2B3 rs3184504 CC, CT, TT 1     12 BRAP rs3782886 CC, CT, TT 1     14 PSMA6   17 ITGB3 rs5918 CC, CT, TT 1     20 MMP9 rs3918242 CC, CT, TT       rs17576 AA, AG, GG 1   22 FLJ25967 rs2331291 Myocardial infarction (early onset) 1 intergenic rs646776 CC, CT, TT 1 ?   1 MIA3 rs17465637 AA, AC, CC 1 ?   1 intergenic rs11206510 CC, CT, TT 1 ?   2 WDR12 rs6725887 CC, CT, TT 1     10 intergenic rs1746048 CC, CT, TT 1 ? Peripheral Arterial Disease 3 MRAS rs2306374 CC, CT, TT 1   15 CHRNA5 rs951266 CC, CT, TT     15 CHRNA3 rs1051730 AA, AG, GG 1, 2 Pre-eclampsia 1 AGT rs4762 CC, CT, TT 1   3 AGTR1 rs5186 AA, AC, CC 1   7 NOS3 rs1799983 GG, GT, TT 1   9 TLR4 rs4986790 AA, AG, GG 1   Stroke 1 F5 rs7542281 1 SNPedia   rs2269648 1         rs2420369           rs6025 AA, AG, GG 1     2 PROC rs1401296 1     3 SERPINI1 rs6797312 AA, AT, TT     9 intergenic rs10757278 AA, AG, GG 1     10 CYP51A1 rs1041296 1     12 GNB3 rs5443 CC, CT, TT 1     14 PRKCH rs2230500 AA, AG, GG 1         rs3783799       19 ICAM1 rs5030341     20 THBD rs1042580 1   Venous Thromboembolism 1 F5 rs6025 AA, AG, GG 1, 2   1 F2 rs1799963 AA, AG, GG   1 SELE rs5361 AA, AC, CC 1   1 LPL rs268 AA, AG, GG 1   5 ADRB2 rs1042714 CC, CG, GG 1     11 F2 i3002432 AA, AG, GG 1   Site Sections Europe Directory Europe Forum Europe Photo Gallery Maps of Europe European Friend Finder Sitemap Travel Guides Europe Guide Belgium Guide England Guide France Guide Germany Guide Netherlands Guide Forum Sections European News EU politics & government European Economy Travelling in Europe European history European food Webmasters About Eupedia Advertising Contact Europe Banner Exchange Privacy Statement Terms of Use Copyright © 2004-2009 Eupedia All Rights Reserved About Eupedia - Privacy Statement - Terms of Use - Contact - Advertising - Sitemap