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Thread: How to interpret admixture proportions percentage on chromosomes

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    How to interpret admixture proportions percentage on chromosomes



    How do you interpret the admixture proportion percentage on each chromosome? For example is there any significance as to which chromosome has the largest percentage? (i.e. chromosome 22 has 40% West Asian but chromosome 16 has only 6%). Does this mean one would share 40% of DNA from this particular marker?

    Any feedback would be appreciated

    Thank you

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    Quote Originally Posted by Christos View Post
    How do you interpret the admixture proportion percentage on each chromosome? For example is there any significance as to which chromosome has the largest percentage? (i.e. chromosome 22 has 40% West Asian but chromosome 16 has only 6%). Does this mean one would share 40% of DNA from this particular marker?

    Any feedback would be appreciated

    Thank you

    doug mcdonald from BGA is the best to do your personnel admixture ( and its free )..mine is below , supplied by doug

    top half is paternal lines
    bottom half is maternal lines


    Uploaded with ImageShack.us

    the other programs calculate your markers with what other people have registered in databases.
    That is the more people test in an area the more accurate these programs are.



    Chr01 is from both your grand parents on both sides ...so you get one segment from one, then another segment from another then another.....there are only 4 segments.
    each segment is further divided going back to the next generation, most segment should stop at 7cM , below this they are irrelevant.


    ChrX is the ancient female line and also is the medical side of a person. The BGA via doug will have migrational zones , the south-asia represent anywhere in eastern europe and the middle-east represents south-west and west-asian regions

    x- chromosome
    http://freepages.genealogy.rootsweb....%206%20gen.pdf

    http://freepages.genealogy.rootsweb....%205%20gen.pdf


    in regards to chr02 to chr22 I do not know anything about...i am still looking

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    Chr07

    father passes one of his number 7 chromosomes intact, his two number 7 chromosomes are shuffled together forming a new chromosome that gets passed down. The mother does the same. So the child receives one number 7 chromosome from each parent, but each of those chromosomes is a mixture of the parent’s two number 7 chromosomes. By this means, genetic information on all the autosomes from all the grandparents get passed down.

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    @zanipolo I had my data analyzed by both 23andme; Dr. McDonald and GEDmatch. I have included my admixture as provided by GEDmatch. I suppose what I am asking is, do the percentages on each marked chromosome bear any specific relevance? In addition, when reading a chromosome painting, is the larger cm the most relevant; you mentioned any segment 7cm or smaller are considered irrelevant. Thanks for your feedback. MDLP World-22 Admixture Proportions Magnus Ducatus Lituaniae Project MDLP World-22 Populations
    Population Chr--> 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
    Pygmy - - - - - - - - - - - 1.1% - - - - - - - - - -
    West-Asian 13.5% 19.2% 20.6% 5.1% 14.2% 10.0% 17.1% 16.5% 18.2% 6.4% 12.7% 15.5% 6.9% 12.1% 19.8% 17.8% 12.3% 6.3% 33.4% 9.0% 12.3% 21.9%
    North-European-Mesolithic - 5.0% - 5.4% 3.4% 5.2% - - 6.2% 1.8% 3.1% 2.0% 8.7% 4.0% - - 6.0% - 1.8% 11.0% 1.8% -
    Indo-Tibetan 1.0% - - 2.9% 0.8% - 4.3% - - - - - - - - - - 1.9% - - - -
    Mesoamerican - - - - - - - - - - - 0.4% - - - - 0.5% - - - - 1.4%
    Arctic-Amerind - - - 2.6% - - - - - - 3.0% - - 0.2% 2.9% 1.2% - - - 0.2% 6.5% -
    South-America_Amerind - 0.6% - - 1.1% 0.6% - 0.1% 1.2% - - 0.1% - - 0.3% - - 2.4% - - - -
    Indian - - - - - - - - - 2.9% - - - - - - 4.0% - - - - -
    North-Siberean - - 0.6% - - - 1.9% - - - - - - 1.8% - - - - - - - -
    Atlantic_Mediterranean_Neolithic 34.5% 21.7% 35.0% 35.8% 26.9% 25.0% 23.4% 19.4% 23.0% 24.5% 25.6% 34.3% 31.2% 23.0% 39.5% 25.3% 22.7% 34.9% 24.4% 34.9% 29.0% 9.0%
    Samoedic - - - - - - - - - - - - - - 1.1% - - - - - - -
    Indo-Iranian 2.6% 0.5% - 2.8% - - - 1.4% - - - 6.7% - 1.1% - - - - 0.6% - - 6.5%
    East-Siberean - - - - 1.3% 0.5% - - - - - - - - - - - - 2.3% - - -
    North-East-European 41.6% 37.7% 37.7% 38.8% 38.0% 41.2% 37.6% 62.6% 35.5% 48.2% 42.7% 38.0% 43.6% 41.4% 25.8% 46.9% 34.9% 50.5% 31.8% 38.6% 41.4% 43.7%
    South-African - - 2.2% - 0.7% - - - 0.6% - 0.9% - - - - 1.5% - - 0.9% - - -
    North-Amerind - - - - - - - - - - - - - - - - - - - - - -
    Sub-Saharian - - - - - - - - 1.2% - - - - 1.1% 0.8% - 1.5% - - 1.2% - -
    East-South-Asian - 0.2% - - - - - - - - - - - - - - - - - - - -
    Near_East 6.7% 11.3% 3.9% 3.3% 13.0% 17.5% 15.7% - 11.7% 16.3% 12.1% 1.9% 9.1% 10.9% 7.1% 7.2% 16.3% 1.2% 5.0% 1.4% 9.0% 12.5%
    Melanesian - - - - 0.5% - - - - - - - 0.6% 4.4% 0.8% - - 2.7% - - - -
    Paleo-Siberian - 3.8% - 1.2% - - - - - - - - - - 0.6% - - - - 0.7% - 1.3%
    Austronesian - - - 2.1% - - - - 2.3% - - - - - 1.3% - 1.9% 0.1% - 3.1% - 3.7%
    Number of SNPs eval: 5994 5874 5094 4511 4417 4787 4306 4044 3754 4208 3678 3767 2960 2694 2505 2679 2428 2442 1899 2397 1360 1415


    Finished.

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    McDonald Painting Full_20130414080333BGA1.jpg@zanipolo I included my chromosome painting as provided my Dr. McDonald. Since my paternal haplogroup has been designated J2a1b*-M67, am I correct in reading that the Middle East segment(s) can actually be Caucasian, where J2 originated?

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    Country: Germany - Baden-Wurttemberg



    You have to add all the figures of a Population together and than divide by 22 (number of chromosomes);
    That will determine your average percentage (frequency) of each population admixture;

    So every value has a relevance, but only the calculated average (all 22 chr.) will reveal the full significance of the values (combined);

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    Quote Originally Posted by Christos View Post
    @zanipolo I had my data analyzed by both 23andme; Dr. McDonald and GEDmatch. I have included my admixture as provided by GEDmatch. I suppose what I am asking is, do the percentages on each marked chromosome bear any specific relevance? In addition, when reading a chromosome painting, is the larger cm the most relevant; you mentioned any segment 7cm or smaller are considered irrelevant. Thanks for your feedback. MDLP World-22 Admixture Proportions Magnus Ducatus Lituaniae Project MDLP World-22 Populations
    Population Chr--> 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
    Pygmy - - - - - - - - - - - 1.1% - - - - - - - - - -
    West-Asian 13.5% 19.2% 20.6% 5.1% 14.2% 10.0% 17.1% 16.5% 18.2% 6.4% 12.7% 15.5% 6.9% 12.1% 19.8% 17.8% 12.3% 6.3% 33.4% 9.0% 12.3% 21.9%
    North-European-Mesolithic - 5.0% - 5.4% 3.4% 5.2% - - 6.2% 1.8% 3.1% 2.0% 8.7% 4.0% - - 6.0% - 1.8% 11.0% 1.8% -
    Indo-Tibetan 1.0% - - 2.9% 0.8% - 4.3% - - - - - - - - - - 1.9% - - - -
    Mesoamerican - - - - - - - - - - - 0.4% - - - - 0.5% - - - - 1.4%
    Arctic-Amerind - - - 2.6% - - - - - - 3.0% - - 0.2% 2.9% 1.2% - - - 0.2% 6.5% -
    South-America_Amerind - 0.6% - - 1.1% 0.6% - 0.1% 1.2% - - 0.1% - - 0.3% - - 2.4% - - - -
    Indian - - - - - - - - - 2.9% - - - - - - 4.0% - - - - -
    North-Siberean - - 0.6% - - - 1.9% - - - - - - 1.8% - - - - - - - -
    Atlantic_Mediterranean_Neolithic 34.5% 21.7% 35.0% 35.8% 26.9% 25.0% 23.4% 19.4% 23.0% 24.5% 25.6% 34.3% 31.2% 23.0% 39.5% 25.3% 22.7% 34.9% 24.4% 34.9% 29.0% 9.0%
    Samoedic - - - - - - - - - - - - - - 1.1% - - - - - - -
    Indo-Iranian 2.6% 0.5% - 2.8% - - - 1.4% - - - 6.7% - 1.1% - - - - 0.6% - - 6.5%
    East-Siberean - - - - 1.3% 0.5% - - - - - - - - - - - - 2.3% - - -
    North-East-European 41.6% 37.7% 37.7% 38.8% 38.0% 41.2% 37.6% 62.6% 35.5% 48.2% 42.7% 38.0% 43.6% 41.4% 25.8% 46.9% 34.9% 50.5% 31.8% 38.6% 41.4% 43.7%
    South-African - - 2.2% - 0.7% - - - 0.6% - 0.9% - - - - 1.5% - - 0.9% - - -
    North-Amerind - - - - - - - - - - - - - - - - - - - - - -
    Sub-Saharian - - - - - - - - 1.2% - - - - 1.1% 0.8% - 1.5% - - 1.2% - -
    East-South-Asian - 0.2% - - - - - - - - - - - - - - - - - - - -
    Near_East 6.7% 11.3% 3.9% 3.3% 13.0% 17.5% 15.7% - 11.7% 16.3% 12.1% 1.9% 9.1% 10.9% 7.1% 7.2% 16.3% 1.2% 5.0% 1.4% 9.0% 12.5%
    Melanesian - - - - 0.5% - - - - - - - 0.6% 4.4% 0.8% - - 2.7% - - - -
    Paleo-Siberian - 3.8% - 1.2% - - - - - - - - - - 0.6% - - - - 0.7% - 1.3%
    Austronesian - - - 2.1% - - - - 2.3% - - - - - 1.3% - 1.9% 0.1% - 3.1% - 3.7%
    Number of SNPs eval: 5994 5874 5094 4511 4417 4787 4306 4044 3754 4208 3678 3767 2960 2694 2505 2679 2428 2442 1899 2397 1360 1415


    Finished.
    The Gedmatch results means that 13.5% of your Chr01 which is west-asian matches 13.5% of others in the data-base with similar genes in that chromosome.

    doug gave you your personnel one...what was that?

    For me ,
    he stated Ancient old northern yugoslavian lands
    Most likely fit is 100% Europe (various subcontinents)
    The following are possible population sets and their fractions,
    most likely at the top
    English= 0.341 Tuscan= 0.659 or
    French= 0.493 Tuscan= 0.507 or
    Irish= 0.271 Tuscan= 0.729 or
    Spain= 0.522 Romania= 0.478 or
    Hungary= 0.239 Italian= 0.761

    I think I can choose which I prefer.

    I asked him what was tuscan and Italian...he said, tuscan is central italian, italian is north italian and greek was south italian

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    Quote Originally Posted by Christos View Post
    McDonald Painting Full_20130414080333BGA1.jpg@zanipolo I included my chromosome painting as provided my Dr. McDonald. Since my paternal haplogroup has been designated J2a1b*-M67, am I correct in reading that the Middle East segment(s) can actually be Caucasian, where J2 originated?
    interesting bar chart...doug said mine was boring, very old...LOL

    unsure, I think south caucasus is west-asian and north-caucasus is european/caucusus.......I need to check. but middle-east is irak, syria, jordan etc

    your maternal looks like middle-east and paternal is european ( caucasus)...so yes you can be from the caucasus........Doug must of given you some options

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    @zanipolo I included data from both GEDmatch (above) and here is McDonald's admix. The Ashkenazi (Jewish) could be considered "noise" as its called. There is no family history. @nobody1 thank you for the fine explanation! This works best with a custom fit:

    Italian 0.4584 Lithuania 0.3369 Jewish 0.2047 or
    Italian 0.3801 Poland 0.4175 Jewish 0.2024 or
    Italian 0.4521 Belorus 0.3831 Jewish 0.1648 or
    French 0.3752 Poland 0.3460 Jewish 0.2787 or
    French 0.4374 Lithuania 0.2693 Jewish 0.2934 or
    Poland 0.4245 Spain 0.3258 Jewish 0.2497 or
    Spain 0.0988 Hungary 0.7041 Jewish 0.1971 or
    French 0.4332 Belorus 0.3065 Jewish 0.2603 or
    Basque 0.0431 Hungary 0.7437 Jewish 0.2131 or
    Italian 0.1062 Hungary 0.7073 Jewish 0.1864 or
    French 0.1158 Hungary 0.6724 Jewish 0.2118 or
    Tuscan 0.0903 Hungary 0.7269 Jewish 0.1828 or
    Basque 0.0375 Germany 0.6580 Jewish 0.3045 or
    French 0.3207 Belorus 0.3671 Sephardic 0.3122 or
    English 0.0771 Hungary 0.6964 Jewish 0.2266

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    Quote Originally Posted by Christos View Post
    @zanipolo I included data from both GEDmatch (above) and here is McDonald's admix. The Ashkenazi (Jewish) could be considered "noise" as its called. There is no family history. @nobody1 thank you for the fine explanation! This works best with a custom fit:

    Italian 0.4584 Lithuania 0.3369 Jewish 0.2047 or
    Italian 0.3801 Poland 0.4175 Jewish 0.2024 or
    Italian 0.4521 Belorus 0.3831 Jewish 0.1648 or
    French 0.3752 Poland 0.3460 Jewish 0.2787 or
    French 0.4374 Lithuania 0.2693 Jewish 0.2934 or
    Poland 0.4245 Spain 0.3258 Jewish 0.2497 or
    Spain 0.0988 Hungary 0.7041 Jewish 0.1971 or
    French 0.4332 Belorus 0.3065 Jewish 0.2603 or
    Basque 0.0431 Hungary 0.7437 Jewish 0.2131 or
    Italian 0.1062 Hungary 0.7073 Jewish 0.1864 or
    French 0.1158 Hungary 0.6724 Jewish 0.2118 or
    Tuscan 0.0903 Hungary 0.7269 Jewish 0.1828 or
    Basque 0.0375 Germany 0.6580 Jewish 0.3045 or
    French 0.3207 Belorus 0.3671 Sephardic 0.3122 or
    English 0.0771 Hungary 0.6964 Jewish 0.2266
    Your
    Italian 0.3801 Poland 0.4175 Jewish 0.2024
    based on your ethnicity looks good, but it still states 20% jewish


    try to see the oracle_2 part....of MDLP

    mine from MDLP which is part of BGA project, which is doug

    # Population Percent
    1 East_European 14.10
    2 Paleo_Mediterranean 29.29
    3 Iberian 11.23
    4 Caucasian 13.59
    5 Uralic_Permic 0.41
    6 Balto_Finnic 2.28
    7 Paleo_Balkanic 2.47
    8 Celto_Germanic 20.66
    9 Paleo_North_European 0.19
    10 South_Central_Asian 3.74
    11 Volga_Uralic 2.03
    12 Altaic_Turkic 0.00


    Pct. Calc. Option 2

    0 Unable to determine 0.01%
    1 NITAL 47.49% ............north italian
    2 MRD 14.13%.............Mordovian
    3 GER 10.69%.............german
    4 CITAL 8.26%...............central italian
    5 SLV 5.06%...............Slovenian
    6 BASQ 3.49%...............Basque
    7 CRS 3.14%...............cyprus
    8 GYP 2.89%...............gypsy
    9 KSV 2.81%...............Kosovo
    10 FRN 2.03%...............northern france

    Noise means under 4% , basically erred

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    @zanipolo Here are my results of the MDLP World-22 Oracle x Admix Results:

    # Population Percent
    1 Pygmy 0.00
    2 West-Asian 15.64
    3 North-European-Mesolithic 2.99
    4 Indo-Tibetan 0.00
    5 Mesoamerican 0.00
    6 Arctic-Amerind 0.55
    7 South-America_Amerind 0.10
    8 Indian 0.00
    9 North-Siberean 0.00
    10 Atlantic_Mediterranean_Neolithic 28.25
    11 Samoedic 0.00
    12 Indo-Iranian 0.00
    13 East-Siberean 0.25
    14 North-East-European 42.00
    15 South-African 0.04
    16 North-Amerind 0.00
    17 Sub-Saharian 0.10
    18 East-South-Asian 0.00
    19 Near_East 9.85
    20 Melanesian 0.13
    21 Paleo-Siberian 0.10
    22 Austronesian 0.00


    Pct. Calc. Option 2

    0 Unable to determine 0.02%
    1 Bulgarian 32.10%
    2 Croatian 26.89%
    3 Macedonian 19.99%
    4 North-East-European 5.60%
    5 Tadjik 3.88%
    6 Saami 3.11%
    7 Jew-Iran 2.51%
    8 Jordanian 2.30%
    9 Jew_Romania 2.07%
    10 Inkeri 1.52%

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    Quote Originally Posted by Nobody1 View Post
    You have to add all the figures of a Population together and than divide by 22 (number of chromosomes);
    That will determine your average percentage (frequency) of each population admixture;

    So every value has a relevance, but only the calculated average (all 22 chr.) will reveal the full significance of the values (combined);
    But the chromosomes are of different length. Some are 50 and some 250 million base pairs. That mean some contain 5 times more genetic (inheritance) material than others.

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    Quote Originally Posted by Christos View Post
    @zanipolo I included data from both GEDmatch (above) and here is McDonald's admix. The Ashkenazi (Jewish) could be considered "noise" as its called. There is no family history. @nobody1 thank you for the fine explanation! This works best with a custom fit:

    Italian 0.4584 Lithuania 0.3369 Jewish 0.2047 or
    Italian 0.3801 Poland 0.4175 Jewish 0.2024 or
    Italian 0.4521 Belorus 0.3831 Jewish 0.1648 or
    French 0.3752 Poland 0.3460 Jewish 0.2787 or
    French 0.4374 Lithuania 0.2693 Jewish 0.2934 or
    Poland 0.4245 Spain 0.3258 Jewish 0.2497 or
    Spain 0.0988 Hungary 0.7041 Jewish 0.1971 or
    French 0.4332 Belorus 0.3065 Jewish 0.2603 or
    Basque 0.0431 Hungary 0.7437 Jewish 0.2131 or
    Italian 0.1062 Hungary 0.7073 Jewish 0.1864 or
    French 0.1158 Hungary 0.6724 Jewish 0.2118 or
    Tuscan 0.0903 Hungary 0.7269 Jewish 0.1828 or
    Basque 0.0375 Germany 0.6580 Jewish 0.3045 or
    French 0.3207 Belorus 0.3671 Sephardic 0.3122 or
    English 0.0771 Hungary 0.6964 Jewish 0.2266
    You are nicely mixed. True citizen of the world. :)

  14. #14
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    Christos's Avatar
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    Y-DNA haplogroup
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    1 out of 1 members found this post helpful.
    @LeBrok "Citizen of the World", what a thoughtful observation! I suppose we all are really!

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