PDA

View Full Version : Median-Joining Network divergence estimates for Haplogroups



zanipolo
25-07-12, 13:13
I recently was noticing there was a lot of information in regards to Median-Joining Network divergence estimates for certain Haplogroups.
This median from what i can gather can predict when a haplotype entered an area, as an example, T ( old K2) entered cornwall and Wales for the first time in 236 CE, while G2 entered England in 443 BCE. With this we can summise that G2 arrived before the Romans, and T while the Romans where in Britain.

If I understand this can also be used with ancient languages entering an area

http://archiver.rootsweb.ancestry.com/th/read/Y-DNA-HAPLOGROUP-G/2006-10/1160079311

I think only 37 and 67 markers can be used to calculate these "creation" times

http://www.flickr.com/photos/archaeogenetics/277501041/

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0041252

I was wondering if anyone has any knowledge on this topic

sparkey
25-07-12, 17:57
Sure, median joining is a useful tool to build phylogenetic trees, and tends to be one of the more accurate tools (more accurate, than, say, probabilistic clustering, which tends to be a little more prone to incorrect tree construction upon convergence). It doesn't really give TMRCAs by itself, though. By building a phylogenetic tree, it helps pinpoint modals for TMRCA models that use them, or otherwise pinpoint clear clusters, so it can be part of the process, particularly if we want to narrow a haplogroup down to its geographic regional clusters.