Angela
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Two new papers discuss the genetic legacy of the Neanderthals.
This is the link to the Reichs lab paper: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12961.html
It's not open access, but the tables and supplementary information are available at the links below.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12961.html#extended-data
http://www.nature.com/nature/journal/vaop/ncurrent/extref/nature12961-s1.pdf
This is a link to the Vernot et al paper, which is also restricted access:
http://www.sciencemag.org/content/early/2014/01/28/science.1245938
The link for the supplementary information can be found below.
http://www.sciencemag.org/content/suppl/2014/01/28/science.1245938.DC1/Vernot.SM.pdf
Dienekes discusses them here:http://www.dienekes.blogspot.com/2014/01/neandertal-admixture-in-modern-humans.html
http://www.dienekes.blogspot.com/2014/01/resurrecting-neandertal-lineages-vernot.html
My take away from my first go round with the material is that while there were some benefits to the admixture with Neanderthals, there was an undoubted cost both to the people of the time and to us, their descendents: male infertility, type 2 diabetes, Crohn's disease, lupus, rheumatoid arthritis and other auto-immune disorders, biliary cirrhosis and even smoking behavior, although I doubt they were smoking at the time. (this last might have to do with addictive behavior perhaps?)
In addition, there's a discussion of some language issues which we have been selecting against since then. I have to read that section again...it might mean that Neanderthals did indeed have some problems with communication.
Ed. Long term clinical depression is also listed as one of the diseases resulting from the admixture.
This is the link to the Reichs lab paper: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12961.html
It's not open access, but the tables and supplementary information are available at the links below.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12961.html#extended-data
http://www.nature.com/nature/journal/vaop/ncurrent/extref/nature12961-s1.pdf
This is a link to the Vernot et al paper, which is also restricted access:
http://www.sciencemag.org/content/early/2014/01/28/science.1245938
The link for the supplementary information can be found below.
http://www.sciencemag.org/content/suppl/2014/01/28/science.1245938.DC1/Vernot.SM.pdf
Dienekes discusses them here:http://www.dienekes.blogspot.com/2014/01/neandertal-admixture-in-modern-humans.html
http://www.dienekes.blogspot.com/2014/01/resurrecting-neandertal-lineages-vernot.html
My take away from my first go round with the material is that while there were some benefits to the admixture with Neanderthals, there was an undoubted cost both to the people of the time and to us, their descendents: male infertility, type 2 diabetes, Crohn's disease, lupus, rheumatoid arthritis and other auto-immune disorders, biliary cirrhosis and even smoking behavior, although I doubt they were smoking at the time. (this last might have to do with addictive behavior perhaps?)
In addition, there's a discussion of some language issues which we have been selecting against since then. I have to read that section again...it might mean that Neanderthals did indeed have some problems with communication.
Ed. Long term clinical depression is also listed as one of the diseases resulting from the admixture.
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