Jovialis
Advisor
- Messages
- 9,311
- Reaction score
- 5,861
- Points
- 113
- Ethnic group
- Italian
- Y-DNA haplogroup
- R-PF7566 (R-Y227216)
- mtDNA haplogroup
- H6a1b7
Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico
Abstract
"Indigenous populations of the Americas experienced high mortality rates during the early contact period as a result of infectious diseases, many of which were introduced by Europeans. Most of the pathogenic agents that caused these outbreaks remain unknown. Through the introduction of a new metagenomic analysis tool called MALT, applied here to search for traces of ancient pathogen DNA, we were able to identify Salmonella enterica in individuals buried in an early contact era epidemic cemetery at Teposcolula-Yucundaa, Oaxaca in southern Mexico. This cemetery is linked, based on historical and archaeological evidence, to the 1545–1550 CE epidemic that affected large parts of Mexico. Locally, this epidemic was known as ‘cocoliztli’, the pathogenic cause of which has been debated for more than a century. Here, we present genome-wide data from ten individuals for Salmonella entericasubsp. enterica serovar Paratyphi C, a bacterial cause of enteric fever. We propose that S. Paratyphi C be considered a strong candidate for the epidemic population decline during the 1545 cocoliztli outbreak at Teposcolula-Yucundaa."
https://www.nature.com/articles/s41559-017-0446-6
Abstract
"Indigenous populations of the Americas experienced high mortality rates during the early contact period as a result of infectious diseases, many of which were introduced by Europeans. Most of the pathogenic agents that caused these outbreaks remain unknown. Through the introduction of a new metagenomic analysis tool called MALT, applied here to search for traces of ancient pathogen DNA, we were able to identify Salmonella enterica in individuals buried in an early contact era epidemic cemetery at Teposcolula-Yucundaa, Oaxaca in southern Mexico. This cemetery is linked, based on historical and archaeological evidence, to the 1545–1550 CE epidemic that affected large parts of Mexico. Locally, this epidemic was known as ‘cocoliztli’, the pathogenic cause of which has been debated for more than a century. Here, we present genome-wide data from ten individuals for Salmonella entericasubsp. enterica serovar Paratyphi C, a bacterial cause of enteric fever. We propose that S. Paratyphi C be considered a strong candidate for the epidemic population decline during the 1545 cocoliztli outbreak at Teposcolula-Yucundaa."
https://www.nature.com/articles/s41559-017-0446-6
Within five years, as many as 15 million people—an estimated 80 percent of the population—were wiped out in an epidemic the locals named "cocoliztli".
The word means "pestilence" in the Aztec Nahuatl language. Its cause, however, has been in question for nearly 500 years.
https://phys.org/news/2018-01-early-colonial-era-mexican-epidemic.html
Last edited: