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Wheal
10-06-19, 17:24
I would love to hear comments about what you all think about the outcome for Big Y-700 will be from Family Tree DNA. Most specifically, what will it tell us, and will it go back and test to find where the split for the break in earlier snps or will it only test for more downstream snps.

spruithean
10-06-19, 18:25
From what I've heard a few people who have their results have received a fair bit of novel variants. This of course could be important for timing estimations of various Y trees, and depending on how many of those novel variants become defining SNPs it could help refine the tree further. Big Y700 will also be looking through more of the Y-chromosome compared to Big Y and Big Y500, so it will definitely have benefits.

torzio
24-09-19, 19:56
My Y700 changes for myself...................... is that my private markers went from 26 to 40 ...........nothing new ............

Salento
26-09-19, 02:05
My Y700 changes for myself...................... is that my private markers went from 26 to 40 ...........nothing new ............

The Y700 is a big Test :)

What kind of information did you get? ... and do you think that T-Z19945 has another branch? (besides CTS1848).

Did they tell you how many T-Z19945 they found and where?

... too many questions :ashamed2:

torzio
26-09-19, 03:36
The Y700 is a big Test :)

What kind of information did you get? ... and do you think that T-Z19945 has another branch? (besides CTS1848).

Did they tell you how many T-Z19945 they found and where?

... too many questions :ashamed2:

No further matches than what i had...and we will evenrually split off without snp CTS1848

Salento
26-09-19, 04:23
No further matches than what i had...and we will evenrually split off without snp CTS1848

Thanks Torzio :satisfied:

Wheal
30-09-19, 16:55
Thank you both for your comments.

On the two Y-700 tests that I ordered, there have been almost no changes, even in novel snps. On one, no changes at all, on the other 2 new novels. And now another question...

Could radiation treatments change the outcome of the reads, most specifically, on ambiguous results?

Duarte
20-04-20, 00:34
If you want to know your final yDNA branch don't waste your time testing STRs in FTDNA's Y-11, Y-25, Y-35, Y-65, Y-111. Go directly to Big Y-700 to test your SNPs.

In my specific case the FTDNA's Y-11, Y-25, Y-35, Y-65, Y-111 testings pointed my final estimated branch as the R-M269:

https://i.imgur.com/57uzgla.png

I only knew my downstream subclades and my final branch when I test with Big Y-700:
R-M269>R-L23>R-L51>R-P310>R-L151>R-P312>R-ZZ11>R-DF27>R-ZZ12_1>R-FGC78762>R-ZZ19_1>R-Z31644>R-BY2285>R-BY25634>R-FGC35133

https://i.imgur.com/G7LpuTu.png

https://i.imgur.com/nAF1OGS.png

Regards :)

Palermo Trapani
20-04-20, 01:34
Duarte: In regards to Post #8, thanks for the that information. So Family Tree DNA Big Y-700 is the one to get. I will definitely check it out. Thanks so much for your suggestion.

Cheers, PalermoTrapani

Palermo Trapani
20-04-20, 01:53
Duarte: I went to FTDNA.com and reviewed the Big Y-700 test. So if I am reading it correctly, that is a test that I must buy and do.

Duarte
20-04-20, 02:47
Duarte: I went to FTDNA.com and reviewed the Big Y-700 test. So if I am reading it correctly, that is a test that I must buy and do.

Hi Trapani. Big Y-700 is the test that you must buy ;)
It is an expensive test, unfortunately, but it is a definitive test. The other Y tests work with STR (Short Tandem Repeat) and are more useful in genealogical DNA testing in surname DNA projects and has become the prevalent analysis method for determining genetic profiles in forensic cases. They work with repetition frequencies. A short tandem repeat (STR) in DNA occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. An STR is also known as a microsatellite. The pattern can range in length from 2 to 16 base pairs (bp) and is typically in the non-coding intron region. A short tandem repeat polymorphism (STRP) occurs when homologous STR loci differ in the number of repeats between individuals. By identifying repeats of a specific sequence at specific locations in the genome, it is possible to create a genetic profile of an individual. In summary and greatly simplifying, STR-based DNA tests give you an estimate of your yDNA. If you are lucky enough to have many matches, the more accurate your estimate will be. I was unlucky enough to have very few matches over shorter distances and it was only possible to predict that my yDNA was R-M269. A disappointing forecast, considering that the vast majority of Midwestern Europe belongs to this haplogroup. The BIG Y-700, in addition to testing more than 111 STRs, tests the SNPs on your Y chromosome. It is an accurate, state-of-the-art test. I am part of the FTDNA Project R-DF27 and the recommendation is not to waste money on the other Y tests if your intention is to know your final yDNA. If you just want a very upstream forecast, then test the STRs. If you want to confirm your final haplogroup, do BIg Y-700.
Cheers,
Duarte.

Palermo Trapani
20-04-20, 18:13
Hi Trapani. Big Y-700 is the test that you must buy ;)
It is an expensive test, unfortunately, but it is a definitive test. The other Y tests work with STR (Short Tandem Repeat) and are more useful in genealogical DNA testing in surname DNA projects and has become the prevalent analysis method for determining genetic profiles in forensic cases. They work with repetition frequencies. A short tandem repeat (STR) in DNA occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. An STR is also known as a microsatellite. The pattern can range in length from 2 to 16 base pairs (bp) and is typically in the non-coding intron region. A short tandem repeat polymorphism (STRP) occurs when homologous STR loci differ in the number of repeats between individuals. By identifying repeats of a specific sequence at specific locations in the genome, it is possible to create a genetic profile of an individual. In summary and greatly simplifying, STR-based DNA tests give you an estimate of your yDNA. If you are lucky enough to have many matches, the more accurate your estimate will be. I was unlucky enough to have very few matches over shorter distances and it was only possible to predict that my yDNA was R-M269. A disappointing forecast, considering that the vast majority of Midwestern Europe belongs to this haplogroup. The BIG Y-700, in addition to testing more than 111 STRs, tests the SNPs on your Y chromosome. It is an accurate, state-of-the-art test. I am part of the FTDNA Project R-DF27 and the recommendation is not to waste money on the other Y tests if your intention is to know your final yDNA. If you just want a very upstream forecast, then test the STRs. If you want to confirm your final haplogroup, do BIg Y-700.
Cheers,
Duarte.

Thanks. I will get around to doing this one. FTDNA seems like they have multiple test. My guess is their FamilyFInder is just like Ancestry or 23 and Me's autosomal test. They also have a Mtdna test that looks like it does something similar to what the Big &-700. Is that correct?

Great information, thanks again. PalermoTrapani

Duarte
20-04-20, 18:52
Thanks. I will get around to doing this one. FTDNA seems like they have multiple test. My guess is their FamilyFInder is just like Ancestry or 23 and Me's autosomal test. They also have a Mtdna test that looks like it does something similar to what the Big &-700. Is that correct?

Great information, thanks again. PalermoTrapani

Hi Trapani.

FTDNA has three types of mtDNA tests, the most complete being the FMS - Full Mitochondrial Sequence, in addition to also having the auDNA test - Family Finder (Family Ancestry).

With regard to the complete sequencing of the yDNA, I believe that the best tests on the market are the FTDNA’s Big Y-700 and the YSEQ Whole Genome Testing 2.0, IMO.

Cheers :)

Wheal
21-04-20, 15:34
In YFull, my dad has 780 STR results

Duarte
21-04-20, 16:10
In YFull, my dad has 780 STR results

Yes, @Wheal.


Big Y-700 examines 700 short tandem repeats (STR) and over 200K SNPs on the Y chromosome.

The great problem, today, with the Big Y-700 is that for you to be able to generate the BAM file to upload to YFULL, you have to pay an additional amount for it. YSEQ has an agreement with YFULL and generates a BAM file for you at no additional cost. However, the cost of doing YSEQ Whole Genome Testing 2.0 is much higher than the BIG Y-700.

Cheers :)

td120
22-04-20, 23:41
$379(BigY-700) + $139(mtDNA Full Seq) =518 USD (+$100 for BAM file generation)= $618 as of today (promotional)

Yelite 2.1 (Full Genomes Corporation) - $425 (will give you mtDNA result too. FTDNA used to do this but now meticulously deletes all traces of mtdna from their BigY).

Dante Labs x30 can be had <300 USD on promotions. Gives you all of the above + autosomal results and health reports ($$,optional) . For 25$ Yseq will align your result to Hg38 and create a list of usable files -FASTA for the mtDNA result, BAM for the Y-chromosome result that you can upload to YFULL or FGC for analysis (49$) etc.Dante have promised to create a shareable link of the Y-chr. result for easier upload to Yfull but have not kept their promise. The results are downloadable ,but the links are not shareable so one has to either upload to a cloud service or let (yseq or whoever ) temporary access to the results so they can download the necessary files for processing.

http://www.beholdgenealogy.com/blog/?p=3209

https://ydna-warehouse.org/statistics.html

I am not into that technical stuff ..and there are plenty of discussions on the net. Seems like Dante's x30 is the great all-rounder (but you must opt-in to sharing your anonymized result for medical research etc-and there is no "decline" option !) ...and Full Genomes Corporation Yelite>BigY.

FTDNA does not accept other companies' BAM files for upload and this keeps you out of their extensive matching base ...but if your result is an uncommon one you may end up with no matches at all... And then most people upload to Yfull so...

Do some research before making your decision...and yes, doing a Y-chr. FullSeq is inevitable ...skip those STR and snp packs,waste of money.

https://www.fullgenomes.com/

https://us.dantelabs.com/

30X Whole Genome Sequencing Test8 weeks - Standard
USD $299.50
with coupon DNADAY50 (Celebrate DNA DAY) - 50% OFF

Tamakore
20-10-20, 11:35
In 2017 I had a DNA test with 23andMe. My Y haplogroup result was R1b-L21. Since I had already traced my paternal line ancestry back to Ireland in the mid-18th century, that result was not much of a surprise, given the dominance of L21 in Ireland.

I'm considering the Big Y-700 test, but I'm wondering, what extra information would it give me? From my autosomal DNA matches with distant cousins, I'm fairly confident that I have correctly identified my Y DNA ancestor back in the 18th century. He was a Catholic living modestly in a rural parish near Dublin.

Given his location, the Irish Sea Cluster, Z255, seems like my most likely sub-clade of L21. I'm not sure I want to pay for the Big Y-500 just to confirm that, though.

Presumably the Big Y-500 would also identify a deeper sub-clade, but what would that tell me that I couldn't already guess? My Y DNA ancestors probably crossed the English Channel in the third millenium BC when Bell Beakers replaced about 90% of the population of Britain, then crossed the Irish Sea soon after. They have probably lived in Ireland ever since.

I'm mildly interested in knowing my deepest Y sub-clade, but if it's just a string of letters and numbers that has an estimated time of origin and some association with other surnames, then I guess I would have to be interested in that information for it's own sake?

CrazyDonkey
11-12-20, 21:13
No further matches than what i had...and we will evenrually split off without snp CTS1848

Matches: Y-37: 11; Y-700: 116.
Haplogroup: Y-37: I2-M223; Y-700: I2-M284 -> L126 -> Y4751 -> Y31616.

Number of Y-700 matches is dependent on how many have tested from your downstream clades. I'm in Isles-Scotland-Ireland, which had massive migration to U.S., which accounts for a ton of testing.

My private SNPs will form a new branch once others test for them.

kingjohn
14-12-20, 15:39
i am also waiting for my big y700
durate mentioned here that it cost money to upload
the bam file to y full which is indeed bummer:disappointed:

p.s
but i will pay the extra money because yfull anlaysis of the bam
is also very important
and a person could end in an upstream branch of the branch ftdna gave him in the big y700 results:thinking:

Flann Fina
15-12-20, 06:04
i am also waiting for my big y700
durate mentioned here that it cost money to upload
the bam file to y full which is indeed bummer:disappointed:

p.s
but i will pay the extra money because yfull anlaysis of the bam
is also very important
and a person could end in an upstream branch of the branch ftdna gave him in the big y700 results:thinking:


For those who may not have heard, you can still access your Family Tree VCF file for free. According to YFull, they can still use VCF files for age estimations and that there’s very little difference between the two files (Bam & VCF) in that regard. Plus, if you should later decide that you would like to upload your Bam file, YFull says they will do the analysis for free. They have a listing of what they’re able to do with VCF files on their website.

https://www.yfull.com/

kingjohn
15-12-20, 11:01
Thanks👍
But from the link you gave
I see it cost 49$ thats not free🤔
Regards
Adam

Flann Fina
15-12-20, 19:24
That’s the usual cost that YFull charges for an analysis. If you submit a VCF file for analysis and then want to later submit your Bam file, they will do that analysis for free (or for no additional charge).




https://www.yfull.com/static/promo/arrow-mini.png
https://www.yfull.com/static/promo/arrow-mini.png


* FREE charge upgrade of .VCF to .BAM is included Big Y700

kingjohn
15-12-20, 19:45
That’s the usual cost that YFull charges for an analysis. If you submit a VCF file for analysis and then want to later submit your Bam file, they will do that analysis for free (or for no additional charge).


https://www.yfull.com/static/promo/arrow-mini.png
https://www.yfull.com/static/promo/arrow-mini.png


* FREE charge upgrade of .VCF to .BAM is included Big Y700



Ok
So do you think i should wait for my finale big y-700 results bam file
Or to upload a vcf file of 111 str markers
That i saw 2 days ago that i now have. ?
Thanks in advance for answeres:cool-v:


P.s
I think i should wait for my final big y-700 results
And then upload the bam file to yfull

Eochaidh
15-12-20, 21:23
In 2017 I had a DNA test with 23andMe. My Y haplogroup result was R1b-L21. Since I had already traced my paternal line ancestry back to Ireland in the mid-18th century, that result was not much of a surprise, given the dominance of L21 in Ireland.

I'm considering the Big Y-700 test, but I'm wondering, what extra information would it give me? From my autosomal DNA matches with distant cousins, I'm fairly confident that I have correctly identified my Y DNA ancestor back in the 18th century. He was a Catholic living modestly in a rural parish near Dublin.

Given his location, the Irish Sea Cluster, Z255, seems like my most likely sub-clade of L21. I'm not sure I want to pay for the Big Y-500 just to confirm that, though.

Presumably the Big Y-500 would also identify a deeper sub-clade, but what would that tell me that I couldn't already guess? My Y DNA ancestors probably crossed the English Channel in the third millenium BC when Bell Beakers replaced about 90% of the population of Britain, then crossed the Irish Sea soon after. They have probably lived in Ireland ever since.

I'm mildly interested in knowing my deepest Y sub-clade, but if it's just a string of letters and numbers that has an estimated time of origin and some association with other surnames, then I guess I would have to be interested in that information for it's own sake?
If you do take the Big Y, you get information like this below. It connects my family with the 3 Rathlin Island samples(Lara M. Cassidy 2015), down to a group of 8 men living today.
Rathlin Samples:
Rathlin1 2026BC - 1885BC M269>L23>L51>L11>P312>S461>L21>DF13>DF21
Rathlin2 2024BC - 1741BC M269>L23>L51>L11>P312>S461>L21>DF13
Rathlin3 1736BC - 1534BC M269>L23>L51>L11>P312>S461>L21

Down to living men:
M269 R1b1a1b - R-M269 is most common in western Europe.
L23 R1b1a1b1
L51 R1b1a1b1a - Arrived in Western Europe with steppe migrations and its main expansion was from the Lower Rhine. Single Grave Culture
P310 R1b1a1b1a1
L151 R1b1a1b1a1a - Corded Ware Culture. Early Corded Ware and Don Yamnaya are basically identical.
P312 R1b1a1b1a1a2 - Match Single Grave Culture from around the Lower Rhine.
S461 R1b1a1b1a1a2c - Insular Celtic
L21 R1b1a1b1a1a2c1
DF13 R1b1a1b1a1a2c1a - Rathlin
Z39589 R1b1a1b1a1a2c1a1
DF49 R1b1a1b1a1a2c1a1a
S6154 R1b1a1b1a1a2c1a1a1
S476 R1b1a1b1a1a2c1a1a1a
DF23 R1b1a1b1a1a2c1a1a1a1
Z2961 R1b1a1b1a1a2c1a1a1a1a
M222 R1b1a1b1a1a2c1a1a1a1a1 - The Féini and Ulaidh and Gáilióin, i.e., the Laighin.
FGC4077 R1b1a1b1a1a2c1a1a1a1a1b
A725 R1b1a1b1a1a2c1a1a1a1a1b1
S676 A group of 8 living men,
S679 A group of 5 of the 8 living men above.

The notes are mostly from the Eurogenes Blog.

Flann Fina
15-12-20, 22:33
Ok
So do you think i should wait for my finale big y-700 results bam file
Or to upload a vcf file of 111 str markers
That i saw 2 days ago that i now have. ?
Thanks in advance for answeres:cool-v:
P.s
I think i should wait for my final big y-700 results
And then upload the bam file to yfull


Yes, you’ll need to wait until your final Y700 results come in from FTDNA because the VCF that YFull accepts for analysis is the Y700 VCF file. If you plan on purchasing your Bam file from FTDNA for the $99 fee, than you can forget about the Y700 VCF file. For those who don’t want to pay for their Bam File, the Y700 VCF is an option because you can still get that for free from FTDNA and submit it to YFull instead of the Bam file.

The STR VCF file is a different file that can also be uploaded to YFull for free, if you already have an account there, but it doesn’t include all of the SNP information you need. That’s in the completed Y700 VCF file.

Again, if you are planning on purchasing the Bam file from FTDNA, none of the above applies to you. In that case, just upload your Bam file to YFull once it’s ready at FTDNA

kingjohn
16-12-20, 10:03
Thanks for informative answere👍
So this thing is expensive :
370$ big y-700 + 99$ for the bam file from ftdna+ 49$ for yfull upload of the bam file😲

P.s
I wish ftdna would have lowered there prices

Flann Fina
17-12-20, 03:14
Thanks for informative answere������
So this thing is expensive :
370$ big y-700 + 99$ for the bam file from ftdna+ 49$ for yfull upload of the bam file������
P.s
I wish ftdna would have lowered there prices


I agree! Personally, I think the $99 fee for a Bam file is punitive and really should be lowered. I actually think it should never have been imposed but who cares what I think. On the bright side, the Y700 VCF file is pretty robust and from what I’ve heard is far better that the old Y500 VCF file. Which is why I say, it may pay for some to consider uploading the Y700 VCF file to YFull - which you can still get for free from FTDNA - and see how your results turnout. Some of my surname matches have done that and there’s no noticeable difference. Plus, if you ever change your mind and decide to pay the Bam file fee, YFull will still do the analysis for no extra charge.

kingjohn
10-02-21, 16:02
I agree! Personally, I think the $99 fee for a Bam file is punitive and really should be lowered. I actually think it should never have been imposed but who cares what I think. On the bright side, the Y700 VCF file is pretty robust and from what I’ve heard is far better that the old Y500 VCF file. Which is why I say, it may pay for some to consider uploading the Y700 VCF file to YFull - which you can still get for free from FTDNA - and see how your results turnout. Some of my surname matches have done that and there’s no noticeable difference. Plus, if you ever change your mind and decide to pay the Bam file fee, YFull will still do the analysis for no extra charge.


one thing for sure
you need patience of iron :laughing:
i am in the 11th week and still no results yet ...... :sad-2:

p.s
i did get the upgrade from 12 marker to 111 str marker ....
thats giving me some way to predict that i am e-y60961 based on those 111 str markers
but i want to see the the real deal snp's of the big y result to confirm it :thinking:

Duarte
10-02-21, 16:22
one thing for sure
you need patience of iron :laughing:
i am in the 11th week and still no results yet ...... :sad-2:

p.s
i did get the upgrade from 12 marker to 111 str marker ....
thats giving me some way to predict that i am e-y60961 based on those 111 str markers
but i want to see the the real deal snp's of the big y result to confirm it :thinking:

Yes, it’s needed much patience. Below, my historical on BigY-700:



Y-DNA67
Ordered
07/16/2019
992



Y-DNA67
Batched
08/12/2019
992



Y-DNA67
Completed
08/20/2019
992



Big Y Raw Data
Ordered
08/14/2019
993



Big Y Raw Data
Completed
08/14/2019
993



Big Y Raw Data
Batched
08/14/2019
993



Big Y-700
Ordered
08/14/2019
993



Big Y-700
Batched
08/14/2019
993



Big Y-700
Completed
10/26/2019
993

kingjohn
10-02-21, 16:51
Yes, it’s needed much patience. Below, my historical on BigY-700:



Y-DNA67
Ordered
07/16/2019
992



Y-DNA67
Batched
08/12/2019
992



Y-DNA67
Completed
08/20/2019
992



Big Y Raw Data
Ordered
08/14/2019
993



Big Y Raw Data
Completed
08/14/2019
993



Big Y Raw Data
Batched
08/14/2019
993



Big Y-700
Ordered
08/14/2019
993



Big Y-700
Batched
08/14/2019
993



Big Y-700
Completed
10/26/2019
993





wow
that is 2 1/2 months :rolleyes2:

p.s
they write that my results are expected between 15/2- 1/3
i hope to get them before ...:thinking:

Duarte
11-02-21, 20:22
In principle, it is possible to obtain the data for the determination of the haplogroup from the .BAM or .VCF files generated by a laboratory that does the whole genomic sequencing. Yfull accepts the upload of data from the following laboratories for the determination of the haplogroup y further downstream:

NextGen Seq raw data file type

.BAM/.CRAM
.VCF

Testing company

FTDNA Big Y
Full Genomes Inc
YSEQ
Enlighten
Veritas Genetics
BGI
Novogene
23mofang
Dante Labs
WeGene
Yoogene
Nebula Genomics

Flann Fina
11-02-21, 20:51
one thing for sure
you need patience of iron :laughing:
i am in the 11th week and still no results yet ...... :sad-2:

p.s
i did get the upgrade from 12 marker to 111 str marker ....
thats giving me some way to predict that i am e-y60961 based on those 111 str markers
but i want to see the the real deal snp's of the big y result to confirm it :thinking:

While I can’t say this for sure, from past experience that’s an indicator that your full results should be coming along fairly soon. Hopefully!

Good luck!

kingjohn
12-02-21, 06:26
While I can’t say this for sure, from past experience that’s an indicator that your full results should be coming along fairly soon. Hopefully!
Good luck!

I hope so
Thanks for kind words:smile:

P.s
Honestly i think that for such a high price
of 370$ i paid for the big y-700
i think ftdna should do an effort to reduce the long long waiting time for results....
...... :thinking:

Ozzie
16-02-21, 09:21
FTDNA is well known to be slow, and late with results. I don't consider testing 111 STRs of much value, as few men opt for that, so you cannot compare. The thing with STRs that I found valuable is STRs with unusual values, I have one which is 8 when the usual is 14 - 15, and those men who match me on that STR have the same surname as mine, given one is the Italian version from Calabria, but he is the closest to me than even the Maltese ones.

mwauthy
01-04-21, 17:27
I hope so
Thanks for kind words:smile:

P.s
Honestly i think that for such a high price
of 370$ i paid for the big y-700
i think ftdna should do an effort to reduce the long long waiting time for results....
...... :thinking:

When did you get your results? Their website is saying 12-14 weeks these days.

kingjohn
05-04-21, 13:29
When did you get your results? Their website is saying 12-14 weeks these days.

I got results like the dates they say
they(ftdna) are ok,
not going to lie i would have been happy if the process was faster 🤔

P.s
It still ther best spot much more than my origins
In y haplogroup and mtdna they are good :good_job: