PDA

View Full Version : High WHG and distinct HLA signature in the Wartberg Culture of Germany



Angela
01-12-19, 17:01
See:
Alexander Immel et al

https://www.biorxiv.org/content/10.1101/851188v1?rss=1

"The Wartberg culture (WBC, 3,500-2,800 BCE) dates to the Late Neolithic period, a time of important demographic and cultural transformations in western Europe. We perform a genome-wide analysis of 42 individuals who were interred in a WBC collective burial in Niedertiefenbach, Germany (3,300-3,200 cal. BCE). Our results highlight that the Niedertiefenbach population indeed emerged at the beginning of the WBC. This farming community was genetically heterogeneous and carried a surprisingly large hunter-gatherer ancestry component (40%). We detect considerable differences in the human leukocyte antigen gene pool between contemporary Europeans and the Niedertiefenbach individuals whose immune response was primarily geared towards defending viral infections.'






So, maybe the higher WHG we see in some of the later Bronze Age steppe admixed people came from incorporation of people like these?

I wonder why there was selection against viral infections in particular. A hunter-gatherer would certainly be exposed to a lot of non-helpful bacteria as well.

I1a3_Young
01-12-19, 18:18
Hi Angela, some comments here if you would combine:

https://www.eupedia.com/forum/threads/39572-Neolith-DNA-reveal-distinct-ancient-HLA-allele-pool-and-population-transform-in-europ

Angela
01-12-19, 19:46
Hi Angela, some comments here if you would combine:

https://www.eupedia.com/forum/threads/39572-Neolith-DNA-reveal-distinct-ancient-HLA-allele-pool-and-population-transform-in-europ

So sorry.

I didn't add much, so I'll just post a comment on your thread and delete this one.