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Thread: New paper on E - early pastoralists in the African continent

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    1 members found this post helpful.

    New paper on E - early pastoralists in the African continent

    http://gbe.oxfordjournals.org/conten....full.pdf+html

    Haplogroup E, defined by mutation M40, is the most common human Y chromosome clade within Africa. To increase the level of resolution of haplogroup E, we disclosed the phylogenetic relationships among 729 mutations found in 33 haplogroup DE Y-chromosomes sequenced at high coverage in previous studies. Additionally, we dissected the E-M35 subclade by genotyping 62 informative markers in 5,222 samples from 118 worldwide populations. The phylogeny of haplogroup E showed novel features compared to the previous topology, including a new basal dichotomy. Within haplogroup E-M35, we resolved all the previously known polytomies and assigned all the E-M35* chromosomes to 5 new different clades, all belonging to a newly identified subhaplogroup (E-V1515), which accounts for almost half of the E-M35 chromosomes from the Horn of Africa. Moreover, using a Bayesian phylogeographic analysis and a SNP-based approach we localized and dated the origin of this new lineage in the northern part of the Horn, about 12 kya. Time frames, phylogenetic structuring and socio-geographic distribution of E-V1515 and its subclades are consistent with a multi-step demic spread of pastoralism within north-eastern Africa and its subsequent diffusion to sub-equatorial areas. In addition, our results increase the discriminative power of the E-M35 haplogroup for use in forensic genetics through the identification of new ancestry-informative markers.



    http://ethiohelix.blogspot.com.au/20...5-aka-e3b.html
    có che un pòpoło no 'l defende pi ła só łéngua el xe prónto par èser s'ciavo

    when a people no longer dares to defend its language it is ripe for slavery.

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    1 members found this post helpful.
    Thanks for posting Sile. HQ already put a link to it in E-V13 origins thread. I find this part interesting a confirmation of past papers. I will read it in more detail later.

    (quoting) Another striking aspect of ourdating is the previously unappreciated large difference in the age between haplogroup EM215(38.6 kya; 95% CI 31.4-45.9 kya) and its sub-haplogroup E-M35 (25.0 kya; 95% CI20.0-30.0 kya). Within the E-V68 sub-clade, the M78 mutation arose in a time windowbetween 20.3 kya (95% CI 16.2-25.4 kya) and 14.8 kya (95% CI 11.6-18.5 kya), namely theTMRCA for E-V68 and E-M78, respectively. The TMRCA of E-V13 chromosomes (8.1 kya;95% CI 5.6-10.8 kya) is consistent with a previous hypothesis about a post-Neolithicexpansion of this haplogroup in Europe (Cruciani et al 2004; 2007).9un (unquote)

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    2 members found this post helpful.
    As a handy reference, here is the phylogeny for "E" from the paper:
    Trombetta 2015 Phylogeny for E.jpg
    Last edited by Angela; 28-06-15 at 17:00. Reason: Graph was doube posted


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    The Y DNA EM35 is ancient and has Branches African, Mediterranean and European

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