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Thread: Fine Dissection of MtDna HV

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    Fine Dissection of MtDna HV

    Fine Dissection of Human Mitochondrial DNA Haplogroup HV Lineages Reveals Paleolithic Signatures from European Glacial Refugia

    Sara De Fanti et al (Sarno and Metspalu are also listed authors

    See:
    http://journals.plos.org/plosone/art...l.pone.0144391

    Abstract


    "Genetic signatures from the Paleolithic inhabitants of Eurasia can be traced from the early divergent mitochondrial DNA lineages still present in contemporary human populations. Previous studies already suggested a pre-Neolithic diffusion of mitochondrial haplogroup HV*(xH,V) lineages, a relatively rare class of mtDNA types that includes parallel branches mainly distributed across Europe and West Asia with a certain degree of structure. Up till now, variation within haplogroup HV was addressed mainly by analyzing sequence data from the mtDNA control region, except for specific sub-branches, such as HV4 or the widely distributed haplogroups H and V. In this study, we present a revised HV topology based on full mtDNA genome data, and we include a comprehensive dataset consisting of 316 complete mtDNA sequences including 60 new samples from the Italian peninsula, a previously underrepresented geographic area. We highlight points of instability in the particular topology of this haplogroup, reconstructed with BEAST-generated trees and networks. We also confirm a major lineage expansion that probably followed the Late Glacial Maximum and preceded Neolithic population movements. We finally observe that Italy harbors a reservoir of mtDNA diversity, with deep-rooting HV lineages often related to sequences present in the Caucasus and the Middle East. The resulting hypothesis of a glacial refugium in Southern Italy has implications for the understanding of late Paleolithic population movements and is discussed within the archaeological cultural shifts occurred over the entire continent."

    Finally, whole genome sequences.

    mtDna HV1.jpg

    mtDna HV 2.jpg


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    Are these ancient samples or HV distribution is based on current population of Italy? I'm guessing the latter.
    Be wary of people who tend to glorify the past, underestimate the present, and demonize the future.

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    Quote Originally Posted by LeBrok View Post
    Are these ancient samples or HV distribution is based on current population of Italy? I'm guessing the latter.
    You mean that map?
    Sicilians and mainlander Southern Italian phenotype galleries.

    http://italicroots.lefora.com/topic/1111/Re-Groups-of-Sicilians
    http://italicroots.lefora.com/topic/375/Southern-italians-how-we-really-look

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