Here is a map showing the allele frequency of HLA-DR9. It is overall an North Asian HLA type, although it is also found in Lebanon and the Maghreb (but Lebanese do have 1-2% of North Asian DNA associated with Y-DNA haplogroup Q1b). The maximum frequencies are observed among the Saami (7 to 16% depending on the sampling region), then in Volga-Ural ethnic groups such as the Mari (11.5%), Bashkirs (5%), Chuvash (5%) and Tatars (3.5%). In Asia, DR9 peaks in East Siberia (28%) but is also very common in China and Taiwan (10-15% depending on the region).

In eastern and northern Europe HLA-DR9 is strongly correlated with Y-haplogroups N1c and Q1a, and to a lower extent also with with East Asian admixture. This correlation diminishes as we move west and south, but is found at higher frequencies in region with more Nordic/Viking ancestry, including Northwest Iberia (Suebi). The Basques also have a bit more DR9 than the Spanish average and also happen to have 1% of Y-haplogroup Q, although it is unknown where this comes from.

Medical associations

HLA-DR9 is associated with early childhood myastenia gravis.


You can verify if you carry HLA-DR9 by checking your raw data from 23andMe, Geno 2.0 or FamilyFinder. Almost all Europeans belong to the DRB1*09:01 subclade.

- DRB1*09:01 : rs2395185 (T), rs2516049 (C)

You normally need to be positive for both alleles.