Eupedia Forums
Site NavigationEupedia Top > Eupedia Forum & Japan Forum
Results 1 to 5 of 5

Thread: Fat fuels the spread of cancer.

  1. #1
    Advisor Angela's Avatar
    Join Date
    02-01-11
    Posts
    18,725


    Ethnic group
    Italian
    Country: USA - New York



    1 members found this post helpful.

    Fat fuels the spread of cancer.

    See:
    http://www.nature.com/news/fat-fuels...TWT_NatureNews

    The caveat is that the study was done on mice, but that's how most of these initial studies are done.

    I wonder if this ties in to the fact that studies show a correlation between being thin and longevity?


    Non si fa il proprio dovere perchè qualcuno ci dica grazie, lo si fa per principio, per se stessi, per la propria dignità. Oriana Fallaci

  2. #2
    Satyavrata Maciamo's Avatar
    Join Date
    17-07-02
    Location
    Lothier
    Posts
    9,299


    Ethnic group
    Italo-celto-germanic
    Country: Belgium - Brussels



    Not all fats are equal. The bad, cancer causing fats are saturated fats and trans fats. Some fats, like omega-3 fatty acids, CLA (conjugated linoleic acid) and ALA (α-lipoic acid), tend to lower inflammation and have antioxidant properties that could have protective effects against cancer, although evidence is still scarce. Overheating oils, even good oils, will transform them into carcinogenic trans fats.
    My book selection---Follow me on Facebook and Twitter --- My profile on Academia.edu and on ResearchGate ----Check Wa-pedia's Japan Guide
    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
    "What is the use of living, if it be not to strive for noble causes and to make this muddled world a better place for those who will live in it after we are gone?", Winston Churchill.

  3. #3
    Advisor Angela's Avatar
    Join Date
    02-01-11
    Posts
    18,725


    Ethnic group
    Italian
    Country: USA - New York



    Most of the study was based on examining metastasis, or how cancer cells are able to spread throughout the body. These scientists are claiming that cells use fat to fuel the "journey".

    "It is a difficult and hazardous undertaking for a cancer cell to uproot itself, travel through the bloodstream and take hold in an entirely different part of the body. (Non-cancerous cells are often programmed to self-destruct if they leave the tissue they live in.) Researchers have long struggled to understand which cancer cells can manage the feat, and how they do so."

    The tumor cells the scientists examined (ranging from breast to brain to lung etc.) had very high levels of a molecule called CD36, which aids in the absorption of fatty acids, apparently.

    "Benitah and his team found that high CD36 expression was required for metastasis in mice. Antibodies that blocked CD36 — and eliminated its interaction with fatty acids — completely inhibited metastasis, although they did not affect the development of primary tumours."

    The only mention of the effect of a high fat diet on cancer in general was this:
    "
    feeding the mice a high-fat diet led to more and larger tumours in the lymph nodes and lungs — a sign of metastasis — compared with mice on normal diets. Benitah’s team is now carrying out a study that aims to enrol 1,000 people with cancer, profiling lipids in their blood to look for any links to the spread of cancer cells."

    This is the link to the actual paper:
    http://www.nature.com/articles/natur...www.nature.com

    I couldn't find a description of the high fat diet they were giving to the test animals.

  4. #4
    Advisor LeBrok's Avatar
    Join Date
    18-11-09
    Location
    Calgary
    Posts
    10,293

    Y-DNA haplogroup
    R1b Z2109
    MtDNA haplogroup
    H1c

    Ethnic group
    Citizen of the world
    Country: Canada-Alberta



    Quote Originally Posted by Angela View Post
    Most of the study was based on examining metastasis, or how cancer cells are able to spread throughout the body. These scientists are claiming that cells use fat to fuel the "journey".

    "It is a difficult and hazardous undertaking for a cancer cell to uproot itself, travel through the bloodstream and take hold in an entirely different part of the body. (Non-cancerous cells are often programmed to self-destruct if they leave the tissue they live in.) Researchers have long struggled to understand which cancer cells can manage the feat, and how they do so."

    The tumor cells the scientists examined (ranging from breast to brain to lung etc.) had very high levels of a molecule called CD36, which aids in the absorption of fatty acids, apparently.

    "Benitah and his team found that high CD36 expression was required for metastasis in mice. Antibodies that blocked CD36 — and eliminated its interaction with fatty acids — completely inhibited metastasis, although they did not affect the development of primary tumours."

    The only mention of the effect of a high fat diet on cancer in general was this:
    "
    feeding the mice a high-fat diet led to more and larger tumours in the lymph nodes and lungs — a sign of metastasis — compared with mice on normal diets. Benitah’s team is now carrying out a study that aims to enrol 1,000 people with cancer, profiling lipids in their blood to look for any links to the spread of cancer cells."

    This is the link to the actual paper:
    http://www.nature.com/articles/natur...www.nature.com

    I couldn't find a description of the high fat diet they were giving to the test animals.
    In same way many vitamins can be implicated in cancer, as they help cell grow. And cancer is a lump of fast growing cells.
    Be wary of people who tend to glorify the past, underestimate the present, and demonize the future.

  5. #5
    Regular Member
    Join Date
    26-11-16
    Posts
    33


    Country: United States



    Quote Originally Posted by Maciamo View Post
    Not all fats are equal. The bad, cancer causing fats are saturated fats and trans fats. Some fats, like omega-3 fatty acids, CLA (conjugated linoleic acid) and ALA (α-lipoic acid), tend to lower inflammation and have antioxidant properties that could have protective effects against cancer, although evidence is still scarce. Overheating oils, even good oils, will transform them into carcinogenic trans fats.

    Angela's article is talking about fat in the body. So the relationship is flawed, wrong conclusion. If I eat the fat of a wild herbivore, this consumption will not create fat deposits in my body. Most of fat in people is caused by the consumption grains, grain by-products and processed foods. Bad foods = unhealthy bodies = good environment for cancer.

    The real question is why were the fat mice, fat to being with? Not the unsurprisingly results that unhealthy mice were more susceptible to diseases and cancer.

    This study is another typical modern junk science with a predetermine goal that fats = bad.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •