Angela
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Very cool if they're right...
See: Kanix Wang et al...Classification of common human diseases derived from shared genetic and environmental determinants
https://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3931.html
"In this study, we used insurance claims for over one-third of the entire US population to create a subset of 128,989 families (481,657 unique individuals). We then used these data to (i) estimate the heritability and familial environmental patterns of 149 diseases and (ii) infer the genetic and environmental correlations for disease pairs from a set of 29 complex diseases. The majority (52 of 65) of our study's heritability estimates matched earlier reports, and 84 of our estimates appear to have been obtained for the first time. We used correlation matrices to compute environmental and genetic disease classifications and corresponding reliability measures. Among unexpected observations, we found that migraine, typically classified as a disease of the central nervous system, appeared to be most genetically similar to irritable bowel syndrome and most environmentally similar to cystitis and urethritis, all of which are inflammatory diseases."
I don't know why the data about migraines is such a surprise. They should have asked me. I used to suffer lots of migraines, as does my brother to a lesser extent. We inherited it from my mother. The first symptom for me is visual, when I get a corona in one eye. At that point I have no pain...that comes later, along with nausea. I learned that if I took three ibuprofin at that stage, it seemed to short circuit the migraine. I figured it had to have something to do not with pain but with the anti-inflammatory qualities of ibuprofin.
Take a look at this too:
It explains so much when presented in this way:
See: Kanix Wang et al...Classification of common human diseases derived from shared genetic and environmental determinants
https://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3931.html
"In this study, we used insurance claims for over one-third of the entire US population to create a subset of 128,989 families (481,657 unique individuals). We then used these data to (i) estimate the heritability and familial environmental patterns of 149 diseases and (ii) infer the genetic and environmental correlations for disease pairs from a set of 29 complex diseases. The majority (52 of 65) of our study's heritability estimates matched earlier reports, and 84 of our estimates appear to have been obtained for the first time. We used correlation matrices to compute environmental and genetic disease classifications and corresponding reliability measures. Among unexpected observations, we found that migraine, typically classified as a disease of the central nervous system, appeared to be most genetically similar to irritable bowel syndrome and most environmentally similar to cystitis and urethritis, all of which are inflammatory diseases."
I don't know why the data about migraines is such a surprise. They should have asked me. I used to suffer lots of migraines, as does my brother to a lesser extent. We inherited it from my mother. The first symptom for me is visual, when I get a corona in one eye. At that point I have no pain...that comes later, along with nausea. I learned that if I took three ibuprofin at that stage, it seemed to short circuit the migraine. I figured it had to have something to do not with pain but with the anti-inflammatory qualities of ibuprofin.
Take a look at this too:
It explains so much when presented in this way: