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Thread: Geno 2.0 Helix results

  1. #1
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    Y-DNA haplogroup
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    Geno 2.0 Helix results

    Helix says they do gene sequencing rather than genotyping, so I wasn't surprised to get slightly different results than with 23andMe. The haplogroups were the same; J1C2 for mitochondria and R-CTS11962 for Y chromosome-it's a descendant of my 23andMe clade of R-M417 and an ancestor of my Morley predicted L1029 and WeGene YP445. Much less neanderthal than 23andMe, as well. For 23andMe I got 0% Eastern European while Geno was 25%! I can only suggest that it is because they include some German populations in Eastern Europe with Geno that 23andMe does not. The Sicilian portion of my ancestry made more sense with Geno, as I have 8% West Mediterranean and 2% Italy and Southern Europe, as opposed to the 6% generic Southern European and 3% Balkan at 23andMe. The greater component of my ancestry was 64% Northwestern European, a change from the 88% at 23andMe, which, again, I can attribute to the different classifications of German populations. My first reference population was the Dutch, and the second, Germans.

  2. #2
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    Quote Originally Posted by Joey37 View Post
    Helix says they do gene sequencing rather than genotyping, so I wasn't surprised to get slightly different results than with 23andMe. The haplogroups were the same; J1C2 for mitochondria and R-CTS11962 for Y chromosome-it's a descendant of my 23andMe clade of R-M417 and an ancestor of my Morley predicted L1029 and WeGene YP445. Much less neanderthal than 23andMe, as well. For 23andMe I got 0% Eastern European while Geno was 25%! I can only suggest that it is because they include some German populations in Eastern Europe with Geno that 23andMe does not. The Sicilian portion of my ancestry made more sense with Geno, as I have 8% West Mediterranean and 2% Italy and Southern Europe, as opposed to the 6% generic Southern European and 3% Balkan at 23andMe. The greater component of my ancestry was 64% Northwestern European, a change from the 88% at 23andMe, which, again, I can attribute to the different classifications of German populations. My first reference population was the Dutch, and the second, Germans.
    I was actually led to believe the same thing initially.

    Here's the thing, Helix does in fact sequence your DNA, and captures the whole genome. However, when I downloaded my raw data from National Geographic, they're roughly looking at the same amount of SNPs as a company like 23andme does.

    My results were 90% Italian & Southern European, 4% Northwestern European, 4% Northeastern European, and 2% Eastern European. Considering the population of which they're using for "Italian & Southern European" is most likely Southern Italian/Sicilian, 90% makes perfect sense. Basically it means that where I would plot on a PCA, would be pulled "10%" in those directions from their sample Italian population. Not that I actually have those various admixtures from that 10%. Had they used where my family is from in Italy as the sample, I would be closer to 100% "Italian & Southern European".

    Example, my top 3 Dodecad k12b results on gedmatch demonstrate this:

    1 Sicilian_Dodecad @ 4.251447
    2 S_Italian_Sicilian_Dodecad @ 4.351736
    3 C_Italian_Dodecad @ 7.259495

    Every company has different results, based on how they classify their reference samples.
    Last edited by Jovialis; 24-07-18 at 00:45. Reason: spelling

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    Y-DNA haplogroup
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    H12a

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    Geno 2.0 Helix results

    You can download All your Raw Sequencing Data from the main Helix website for a fee ($499).
    Last edited by Salento; 24-07-18 at 03:57. Reason: My results are everywhere already.
    But you oh Messapo, Tamer of Horses ... that no one, with neither iron nor fire can break down! “Virgil”

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    Y-DNA haplogroup
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    A while ago, I was able to reformat the free NatGeo Helix RawData with DnaKitStudio, and load it around.
    some results: (ps I’m IT-Apulian)

    > source('nMonte.R')
    > getMonte('k36.csv', 'resk36.csv')

    [1] "1. CLOSEST SINGLE ITEM DISTANCE%"

    IT_Abruzzo IT_Apulia IT_Lazio Sicily_Trapani Sicily_Agrigento Sicily_Catania GR_Cyclades IT_Campania
    9.611951 10.476163 10.744302 11.052194 11.220150 11.289021 11.330473 11.456571

    ———————

    from an oracle-spreadsheet calculator:






    ———

    From Ged:


    ............

    My NatGeo Helix Results:


    ————

    Also: The downloadable zip file is not opening, maybe they are are working on backward-compatibility.

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    Y-DNA haplogroup
    T1a2 -Z19945
    MtDNA haplogroup
    H12a

    Ethnic group
    Italian
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    5 Population Sharing:


    IT_Apulia 22.72%
    IT_Abruzzo 22.57%
    IT_Lazio 19.14%
    Sicily_Trapani 18.21%
    IT_Campania 17.37%


    (% also located on previous post)

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    Quote Originally Posted by Salento View Post
    5 Population Sharing:


    IT_Apulia 22.72%
    IT_Abruzzo 22.57%
    IT_Lazio 19.14%
    Sicily_Trapani 18.21%
    IT_Campania 17.37%


    (% also located on previous post)
    What test is that?

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    Quote Originally Posted by Jovialis View Post
    What test is that?
    The Helix through an oracle-spreadsheet calculator.
    The Top one is NMonte.

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    Y-DNA haplogroup
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    Quote Originally Posted by Joey37 View Post
    Helix says ...
    Quote Originally Posted by Joey37 View Post
    I am 1/8 Sicilian, so I do not lack Mediterranean ancestry, and much of Sicily was Greek-speaking in the past. For what ... The only part of my ancestry that is non-European is 0.5% Native American. You do the math.

    Compare to My Reference Population:


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    2 members found this post helpful.
    Quote Originally Posted by Salento View Post
    Compare to My Reference Population:

    I'd say The people of Salento, and all Puglesi in general are between Central Italians (Umbria, Lazio, Abbruzzio regions), other Southern Italians, and central Greeks. Gedmatch calculators have placed me there as such.


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    Quote Originally Posted by Jovialis View Post
    I'd say The people of Salento, and all Puglesi in general are between Central Italians (Umbria, Lazio, Abbruzzio regions), other Southern Italians, and central Greeks. Gedmatch calculators have placed me there as such.

    Generally you're right, we have seen the results of the other Pugliesi, and all point in the direction you described. :)

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    Y-DNA haplogroup
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    The General NatGeo-Geno2 Results:


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    1 members found this post helpful.
    Quote Originally Posted by Salento View Post
    Compare to My Reference Population:

    my references


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    2 members found this post helpful.


    That's a shame that they're going out of business. This was the first test I took, that sparked my interest in this hobby. Above are my results.

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