Angela
Elite member
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- Italian
It's a very interesting paper. Why'd they have to drop it now?
See:
Laurits Skov et al
https://www.biorxiv.org/content/biorxiv/early/2018/12/21/503995.full.pdf
"Strong selective sweeps before 45,000BP displaced archaic admixture across the human X chromosome"
"The X chromosome in non-African populations has less diversity and less Neanderthal introgression than expected. We analyzed X chromosome diversity across the globe and discovered seventeen chromosomal regions, where haplotypes of several hundred kilobases have recently reached high frequencies in non-African populations only. The selective sweeps must have occurred more than 45,000 years ago because the ancient Ust'-Ishim male also carries its expected proportion of these haplotypes. Surprisingly, the swept haplotypes are entirely devoid of Neanderthal introgression, which implies that a population without Neanderthal admixture contributed the swept haplotypes. It also implies that the sweeps must have happened after the main interbreeding event with Neanderthals about 55,000 BP. These swept haplotypes may thus be the only genetic remnants of an earlier out-of-Africa event."
From Lazaridis:
"A very intriguing paper by @SkovLaurits et al.. Could Basal Eurasians be the non-Neandertal-admixed pop. that contributed to Ust'Ishim? If so, all non-Africans could have some fixed B.E. ancestry (and a few in the Near East extra B.E. above the baseline)."
See:
Laurits Skov et al
https://www.biorxiv.org/content/biorxiv/early/2018/12/21/503995.full.pdf
"Strong selective sweeps before 45,000BP displaced archaic admixture across the human X chromosome"
"The X chromosome in non-African populations has less diversity and less Neanderthal introgression than expected. We analyzed X chromosome diversity across the globe and discovered seventeen chromosomal regions, where haplotypes of several hundred kilobases have recently reached high frequencies in non-African populations only. The selective sweeps must have occurred more than 45,000 years ago because the ancient Ust'-Ishim male also carries its expected proportion of these haplotypes. Surprisingly, the swept haplotypes are entirely devoid of Neanderthal introgression, which implies that a population without Neanderthal admixture contributed the swept haplotypes. It also implies that the sweeps must have happened after the main interbreeding event with Neanderthals about 55,000 BP. These swept haplotypes may thus be the only genetic remnants of an earlier out-of-Africa event."
From Lazaridis:
"A very intriguing paper by @SkovLaurits et al.. Could Basal Eurasians be the non-Neandertal-admixed pop. that contributed to Ust'Ishim? If so, all non-Africans could have some fixed B.E. ancestry (and a few in the Near East extra B.E. above the baseline)."