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Thread: Population history of indigenous Mexicans

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    Population history of indigenous Mexicans

    See:
    https://academic.oup.com/mbe/advance...medium=twitter

    One of the interesting results is the unusual quantities of certain genes.

    "Native American genetic variation remains underrepresented in most catalogs of human genome sequencing data. Previous genotyping efforts have revealed that Mexico’s indigenous population is highly differentiated and substructured, thus potentially harboring higher proportions of private genetic variants of functional and biomedical relevance. Here we have targeted the coding fraction of the genome and characterized its full site frequency spectrum by sequencing 76 exomes from five indigenous populations across Mexico. Using diffusion approximations, we modeled the demographic history of indigenous populations from Mexico with northern and southern ethnic groups splitting 7.2 kya and subsequently diverging locally 6.5 kya and 5.7 kya, respectively. Selection scans for positive selection revealed BCL2L13 and KBTBD8 genes as potential candidates for adaptive evolution in Rarámuris and Triquis, respectively. BCL2L13 is highly expressed in skeletal muscle and could be related to physical endurance, a well-known phenotype of the northern Mexico Rarámuri. The KBTBD8 gene has been associated with idiopathic short stature and we found it to be highly differentiated in Triqui, a southern indigenous group from Oaxaca whose height is extremely low compared to other Native populations."


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    1 members found this post helpful.
    Quote Originally Posted by Angela View Post
    The KBTBD8 gene has been associated with idiopathic short stature and we found it to be highly differentiated in Triqui, a southern indigenous group from Oaxaca whose height is extremely low compared to other Native populations."
    From Wikipedia:

    https://en.m.wikipedia.org/wiki/Triqui

    "The main sport practiced by the Triqui people is basketball, and as such, a basketball court can be found in all their surrounding communities."


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    Quote Originally Posted by Tomenable View Post
    From Wikipedia:

    https://en.m.wikipedia.org/wiki/Triqui

    "The main sport practiced by the Triqui people is basketball, and as such, a basketball court can be found in all their surrounding communities."

    Well, everything is relative, yes? They're playing against each other, not against the Masai. :)

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