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Thread: Increased fertility for women with Neanderthal gene

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    Increased fertility for women with Neanderthal gene

    "Increased fertility for women with Neanderthal gene, study suggests -- ScienceDaily" https://www.sciencedaily.com/release...0526151738.htm

    "One in three women in Europe inherited the receptor for progesterone from Neandertals -- a gene variant associated with increased fertility, fewer bleedings during early pregnancy and fewer miscarriages. This is according to a study published in Molecular Biology and Evolution by researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and Karolinska Institutet in Sweden."

    Here is the paper.

    "Neandertal Progesterone Receptor | Molecular Biology and Evolution | Oxford Academic" https://academic.oup.com/mbe/advance...saa119/5841671

    "The progesterone receptor is encoded by the PGR gene on chromosome 11."

    "A polymorphic variant of PGR which carries the missense substitution V660L (rs1042838) in exon 4 and an Alu insertion between exons 7 and 8 occurs among present-day populations, reaching frequencies of up to ∼20%."

    The Neanderthal allele is most common among people of European descent. It is rare in East Asia and South Asia.

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    Quote Originally Posted by Coriolan View Post
    "Increased fertility for women with Neanderthal gene, study suggests -- ScienceDaily" https://www.sciencedaily.com/release...0526151738.htm

    "One in three women in Europe inherited the receptor for progesterone from Neandertals -- a gene variant associated with increased fertility, fewer bleedings during early pregnancy and fewer miscarriages. This is according to a study published in Molecular Biology and Evolution by researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and Karolinska Institutet in Sweden."

    Here is the paper.

    "Neandertal Progesterone Receptor | Molecular Biology and Evolution | Oxford Academic" https://academic.oup.com/mbe/advance...saa119/5841671

    "The progesterone receptor is encoded by the PGR gene on chromosome 11."

    "A polymorphic variant of PGR which carries the missense substitution V660L (rs1042838) in exon 4 and an Alu insertion between exons 7 and 8 occurs among present-day populations, reaching frequencies of up to ∼20%."

    The Neanderthal allele is most common among people of European descent. It is rare in East Asia and South Asia.
    Interesting, Coriolan.

    I'm CC. I don't know if that's the "Neanderthal" variant or not.


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    Quote Originally Posted by Angela View Post
    Interesting, Coriolan.

    I'm CC. I don't know if that's the "Neanderthal" variant or not.
    It looks like you have the "normal" result (Homo sapiens'): https://www.snpedia.com/index.php/Rs1042838

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    So the Neanderthal variant increases fertility but also risk for endometrial ovarian cancer...
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