What are these different families of languages? Elamite in the southwest of Iran? Semitic in Mesopotamia and Arabia? Hurro-Urartian in Anatolia and Levant? Kartvelian in the Caucasus?
What was the main language of people who lived in Iran? We just know in south of modern Khuzistan province (about 5% of the total area of Iran) some people spoke Elamite, what about other regions? Indo-Iranian influence on Hurro-Urartian Mitanni came from where?
Mannaeans from the Lake Urmia area probably spoke Kassite (which seems to have been a Hurro-Urartian language or dialect of Hurrian with an Indic superstratum) and later (by after around 1000 BCE) spoke at least one Iranic language (based on personal names, such as Iranzu and especially Bagdatti). There may also have been an early Armenian-speaking population in the region (meaning, prior to 600 BCE--I say this due to the archaeological and genetic data). Urartians are also thought to have come from the northern Iran/Iraq border originally.
The name Mannaea could very likely be an Indo-European or Hurro-Urartian name (a variation of the name was Minyas). Compare to Greek Minos/Minas. Urartian Menuas (the modern Armenian form of the name is Manavaz). Maybe Sanskrit Manu. Maybe Germanic Mannaz.