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Here we introduce a new DNA enrichment assay, coined YMCA (Y-mappable capture assay),
that targets the "mappable" regions of the NRY. We show that compared to low-coverage shotgun
sequencing and 1240K capture, YMCA significantly improves the coverage and number of sites
hit on the NRY, increasing the number of Y-haplogroup informative SNPs, and allowing for the
identification of previously undiscovered variants.
I'm impressed.
that targets the "mappable" regions of the NRY. We show that compared to low-coverage shotgun
sequencing and 1240K capture, YMCA significantly improves the coverage and number of sites
hit on the NRY, increasing the number of Y-haplogroup informative SNPs, and allowing for the
identification of previously undiscovered variants.
I'm impressed.