Eupedia Forums
Site NavigationEupedia Top > Eupedia Forum & Japan Forum
Results 1 to 12 of 12

Thread: Eye Color (Simcoe et al. 2021)

  1. #1
    Advisor Jovialis's Avatar
    Join Date
    04-05-17
    Posts
    5,308

    Y-DNA haplogroup
    R1b1a1a2b1 (R-F1794)
    MtDNA haplogroup
    H6a1b

    Ethnic group
    Italian
    Country: United States



    3 members found this post helpful.

    Eye Color (Simcoe et al. 2021)

    I was taking a look at Nebula Genomics because they offer whole genome sequencing. A study on eye color inheritance they made a chart for, caught my attention.

    Source: Simcoe et al. 2021:

    https://advances.sciencemag.org/content/7/11/eabd1239


  2. #2
    Regular Member
    Join Date
    28-03-20
    Posts
    337


    Country: Austria



    1 members found this post helpful.
    Quote Originally Posted by Jovialis View Post
    I was taking a look at Nebula Genomics because they offer whole genome sequencing. A study on eye color inheritance they made a chart for, caught my attention.

    Source: Simcoe et al. 2021:

    https://advances.sciencemag.org/content/7/11/eabd1239

    That's the easy one, because I know about mixed eyed people which can produce every eye color in their children. Like blue-grey with a just slight tinge of brown, or green with a slight tinge of brown. The offspring of such people can have every eye colour and I think the ratios are not that one sided either. What about the genetics of these? I couldn't find too much about it so far.

  3. #3
    Regular Member
    Join Date
    23-01-21
    Posts
    173

    Y-DNA haplogroup
    R1b-Df27
    MtDNA haplogroup
    T2b3e

    Country: Spain



    I have blue eyes and my parents have brown (although my grandfather and some relatives also have blue eyes). My children 50% blue and brown (my wife brown). When I was a child, at school, Father Zumalacarregui said that Basques with blue eyes were descendants of Vikings, now we know that it is a matter of our ancestors WHGs

  4. #4
    Regular Member torzio's Avatar
    Join Date
    10-05-19
    Location
    Australia
    Posts
    1,865

    Y-DNA haplogroup
    T1a2 - SK1480
    MtDNA haplogroup
    H95a

    Ethnic group
    North Italian
    Country: Australia



    Quote Originally Posted by Riverman View Post
    That's the easy one, because I know about mixed eyed people which can produce every eye color in their children. Like blue-grey with a just slight tinge of brown, or green with a slight tinge of brown. The offspring of such people can have every eye colour and I think the ratios are not that one sided either. What about the genetics of these? I couldn't find too much about it so far.

    how long , in months/years does the child birth colour eyes stay as is and what they end up finally with ?


    my family history below
    my grandsons are both born blue eyes and both changed after 18months ...............3yo is now blue-grey and 2yo is now dark-green with blue rim

    All my sons are all blue eyes

    my wife is blue eye

    I am green eye ( was mid green and with age I am going light green )

    my father is light green....grandfather (1895-1988) is dark green and ...........my great great grandfather (1853-1924) is mid green


    BTW....23andme always give me as 70% blue eye and 30% green eye ............I have no blue
    Fathers mtdna ... T2b17
    Grandfather mtdna ... T1a1e
    Sons mtdna ... K1a4p
    Mum paternal line ... R1b-S8172
    Grandmum paternal side ... I1-Y33791
    Wife paternal line ... R1a-Z282

  5. #5
    Regular Member
    Join Date
    28-03-20
    Posts
    337


    Country: Austria



    Quote Originally Posted by torzio View Post
    how long , in months/years does the child birth colour eyes stay as is and what they end up finally with ?


    my family history below
    my grandsons are both born blue eyes and both changed after 18months ...............3yo is now blue-grey and 2yo is now dark-green with blue rim

    All my sons are all blue eyes

    my wife is blue eye

    I am green eye ( was mid green and with age I am going light green )

    my father is light green....grandfather (1895-1988) is dark green and ...........my great great grandfather (1853-1924) is mid green


    BTW....23andme always give me as 70% blue eye and 30% green eye ............I have no blue
    Eye color changes from birth in the first years, up to the 3rd year of age I'd say.

    But my point was about stable eye colors in adults. Like I know adult people with such blue-grey with a tinge of brown. Its stable. But the inheritance pattern seems to be like half main allel plus a lot of blue eye supportive minor allels. That's the rare case of males which can, even though they are mostly light eyed, can get darker eyed kids even with a light eyed partner. Because they lack one of the main allels, and the light color being also based on the minor ones, which the partner might not have all.

  6. #6
    Regular Member Regio X's Avatar
    Join Date
    12-03-14
    Posts
    1,029


    Country: Italy



    deleted by poster

  7. #7
    Regular Member torzio's Avatar
    Join Date
    10-05-19
    Location
    Australia
    Posts
    1,865

    Y-DNA haplogroup
    T1a2 - SK1480
    MtDNA haplogroup
    H95a

    Ethnic group
    North Italian
    Country: Australia



    I tested with YSEQ

    https://phenotype.yseq.net/index.php


    and with my 23andme v3 ...I get

    Phenotype Probability
    Blue 95%
    Intermediate 3%
    Brown 2%



    same above if I use ftdna

    ............................................

    one of my sons...............23andme v4

    Phenotype Probability
    Blue 91.8%
    Intermediate 4.8%
    Brown 3.4%

  8. #8
    Advisor Angela's Avatar
    Join Date
    02-01-11
    Posts
    19,193


    Ethnic group
    Italian
    Country: USA - New York



    2 members found this post helpful.
    I haven't gone through the whole Supplement but I haven't seen that chart yet. It might not represent the opinion of the authors. Eye color is very complicated, governed by a lot of smaller effect newly discovered genes as well as the bigger ones of which we were aware.

    Just be experience, I can say the chart is very simplified. My father's parents were both light eyed, with my nonna having hazel green eyes, and my nonno eyes as blue as a summer sky. Not one of their eleven children got blue eyes. All had some combination of grey, green, and light hazel.

    I published this explanation for how two blue eyed people can indeed have a brown eyed child years ago, although the odds are against it.

    https://www.scienceofbiogenetics.com...ue-eyed-child/

    Oh, another life example from my husband's mother and father. A very dark brown eyed mother who happened to have a blue eyed mother, who then marries a man with green/hazel eyes can give birth to a light brown eyed son and a bright blue-eyed daughter. Since the daughter also had blonde hair and the mother had black hair, she was often asked if she adopted her daughter. :)


    Non si fa il proprio dovere perchè qualcuno ci dica grazie, lo si fa per principio, per se stessi, per la propria dignità. Oriana Fallaci

  9. #9
    Advisor Jovialis's Avatar
    Join Date
    04-05-17
    Posts
    5,308

    Y-DNA haplogroup
    R1b1a1a2b1 (R-F1794)
    MtDNA haplogroup
    H6a1b

    Ethnic group
    Italian
    Country: United States



    I'm interested in seeing my child's eye color. My eyes are dark, my wife's eyes are green. I wonder who they will take after. My mom's eyes are dark like mine, my dad's eyes are hazel. My mother-in-law has blue eyes, and my father-in-law has wine colored eyes.

  10. #10
    Regular Member torzio's Avatar
    Join Date
    10-05-19
    Location
    Australia
    Posts
    1,865

    Y-DNA haplogroup
    T1a2 - SK1480
    MtDNA haplogroup
    H95a

    Ethnic group
    North Italian
    Country: Australia



    Quote Originally Posted by torzio View Post
    I tested with YSEQ

    https://phenotype.yseq.net/index.php


    and with my 23andme v3 ...I get

    Phenotype Probability
    Blue 95%
    Intermediate 3%
    Brown 2%



    same above if I use ftdna

    ............................................

    one of my sons...............23andme v4

    Phenotype Probability
    Blue 91.8%
    Intermediate 4.8%
    Brown 3.4%

    another predictor

    https://hirisplex.erasmusmc.nl/

  11. #11
    Elite member
    Join Date
    23-02-15
    Location
    Groningen
    Posts
    1,149

    Y-DNA haplogroup
    E1b1b/ E-V22

    Ethnic group
    North Sea Germanic
    Country: Netherlands



    Quote Originally Posted by torzio View Post
    I tested with YSEQ

    https://phenotype.yseq.net/index.php


    and with my 23andme v3 ...I get

    Phenotype Probability
    Blue 95%
    Intermediate 3%
    Brown 2%



    same above if I use ftdna

    ............................................

    one of my sons...............23andme v4

    Phenotype Probability
    Blue 91.8%
    Intermediate 4.8%
    Brown 3.4%
    Or the FTDNA files are not suitable or this model is not accurat....produces only HEINO results!!!






  12. #12
    Elite member
    Join Date
    23-02-15
    Location
    Groningen
    Posts
    1,149

    Y-DNA haplogroup
    E1b1b/ E-V22

    Ethnic group
    North Sea Germanic
    Country: Netherlands



    1 members found this post helpful.
    Quote Originally Posted by Jovialis View Post
    I'm interested in seeing my child's eye color. My eyes are dark, my wife's eyes are green. I wonder who they will take after. My mom's eyes are dark like mine, my dad's eyes are hazel. My mother-in-law has blue eyes, and my father-in-law has wine colored eyes.

    This publication has a pretty accurate chard:
    https://www.nature.com/articles/nbt....tcallback=true

    https://images.app.goo.gl/SRnEHaSdV98gjqvC8

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •