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Thread: First Bronze Age Human Mitogenomes from Calabria, Grotta Della Monaca, Southern Italy

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    Moderator Pax Augusta's Avatar
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    First Bronze Age Human Mitogenomes from Calabria, Grotta Della Monaca, Southern Italy

    First Bronze Age Human Mitogenomes from Calabria (Grotta Della Monaca, Southern Italy)

    Genes 2021, 12(5), 636; https://doi.org/10.3390/genes12050636

    Abstract: The Italian peninsula was host to a strong history of migration processes that shaped its
    genomic variability since prehistoric times. During the Metal Age, Sicily and Southern Italy were
    the protagonists of intense trade networks and settlements along the Mediterranean. Nonetheless,
    ancient DNA studies in Southern Italy are, at present, still limited to prehistoric and Roman Apulia.
    Here, we present the first mitogenomes from a Middle Bronze Age cave burial in Calabria to address
    this knowledge gap. We adopted a hybridization capture approach, which enabled the recovery
    of one complete and one partial mitochondrial genome. Phylogenetic analysis assigned these two
    individuals to the H1e and H5 subhaplogroups, respectively. This preliminary phylogenetic analysis
    supports affinities with coeval Sicilian populations, along with Linearbandkeramik and Bell Beaker
    cultures maternal lineages from Central Europe and Iberia. Our work represents a starting point
    which contributes to the comprehension of migrations and population dynamics in Southern Italy,
    and highlights this knowledge gap yet to be filled by genomic studies.


  2. #2
    Regular Member kingjohn's Avatar
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    1 members found this post helpful.
    Thanks pax augusta for sharing
    very interesting

    P.s
    I hope for y haplogroups also
    One day from this site
    https://www.yfull.com/tree/E-FGC7391/

    https://yfull.com/mtree/H3ap/

  3. #3
    Advisor Jovialis's Avatar
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    Great find,

    Strangely, I tried looking up the study on ENA and GenBank, but it doesn't seem like they have up yet. I will keep an eye out for it.

    ENA (Accession number: PRJEB44125)

    NCBI GenBank (Accession number: MW853672)

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    Moderator Pax Augusta's Avatar
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    Quote Originally Posted by Jovialis View Post
    Great find,

    Strangely, I tried looking up the study on ENA and GenBank, but it doesn't seem like they have up yet. I will keep an eye out for it.

    ENA (Accession number: PRJEB44125)

    NCBI GenBank (Accession number: MW853672)

    Jovialis, please check but it seems only mitogenome, not autosomal DNA

    https://www.ebi.ac.uk/ena/browser/view/PRJEB44125

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    Advisor Jovialis's Avatar
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    ^^I have already checked them out, and unfortunately, they cannot be used to analyze with any calculators for autosomal analysis.

  6. #6
    Moderator Pax Augusta's Avatar
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    Quote Originally Posted by Jovialis View Post
    ^^I have already checked them out, and unfortunately, they cannot be used to analyze with any calculators for autosomal analysis.
    Likely autosomal analysis is missing.

  7. #7
    Advisor Jovialis's Avatar
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    Quote Originally Posted by Pax Augusta View Post
    Likely autosomal analysis is missing.
    Actually, I was confused when I answered you. My recollection was that they are in GZ format, which I am not clear how to extract from. Nevertheless, the files are tiny, so I am assuming they will not process.

    If anyone could extract them from GZ format, we can see. There is a way to convert the files to BAM format, using PGDSpider2, but I never figured out how to use that tool.

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