Hi there,
I'm not even sure I'm in the right shop here. I got into the DNA testing for geneology but I've kind of got hooked on the health side of things at the moment.
I looked all over for a forum that might answer the question as to why does a report from Promothease list more results for a simple Ancestry.com DNA test than for a whole genome read from Nebula, one at much greater coverage and many times the depth.
Why would Promothease be seeing way more variations with the Ancestry test that has less coverage and depth? The difference is huge with the Nebula data returning +17000 variants and the Ancestry data offering +50000. Curiously the vast bulk of the extra SNPs/genosets are 'good' and highlighted in green.
I'd like to understand what's going on there exactly. I've imagined some stuff but I'm pretty much a novice at genomics and bioinformatics and could be barking up the wrong tree. Thanks.
I'm not even sure I'm in the right shop here. I got into the DNA testing for geneology but I've kind of got hooked on the health side of things at the moment.
I looked all over for a forum that might answer the question as to why does a report from Promothease list more results for a simple Ancestry.com DNA test than for a whole genome read from Nebula, one at much greater coverage and many times the depth.
Why would Promothease be seeing way more variations with the Ancestry test that has less coverage and depth? The difference is huge with the Nebula data returning +17000 variants and the Ancestry data offering +50000. Curiously the vast bulk of the extra SNPs/genosets are 'good' and highlighted in green.
I'd like to understand what's going on there exactly. I've imagined some stuff but I'm pretty much a novice at genomics and bioinformatics and could be barking up the wrong tree. Thanks.