A study of genetic diversity of three isolated populations in Xinjiang using Y-SNP

[Gao1111]

Y-chromosome of 179 individuals in these three isolated populations, all mutations and SNPs inthe Y-chromosome and their corresponding haplotypes were obtained. Types and frequencies ofeach haplotype were analyzed to investigate genetic diversity and genetic structure in the threeisolated populations. The results showed that 12 haplogroups were detected in the Keriyan withhigh frequencies of the J2a1b1 (25.64%), R1a1a1b2a (20.51%), R2a (17.95%) and R1a1a1b2a2(15.38%) groups. Sixteen haplogroups were noted in the Lopnur with the following frequencies:J2a1 (43.75%), J2a2 (14.06%), R2 (9.38%) and L1c (7.81%). Forty haplogroups were foundin the Dolan, noting the following frequencies: R1b1a1a1 (9.21%), R1a1a1b2a1a (7.89%),R1a1a1b2a2b (6.58%) and C3c1 (6.58%). These data show that these three isolated populationshave a closer genetic relationship with the Uygur, Mongolian and Sala peoples. In particular,there are no significant differences in haplotype and frequency between the three isolatedpopulations and Uygur (f=0.833, p=0.367). In addition, the genetic haplotypes and frequencies inthe three isolated populations showed marked Eurasian mixing illustrating typical characteristicsof Central Asian populations.


http://www.ivpp.cas.cn/cbw/rlxxb/xbwzxz/201805/P020180515379362334965.pdf