I've opined a lot on the Etruscans here and on other sites in the past, because the Etruscans are sort of a thing with me (and with other people), and I've spent a very long time studying them, but at the end of the day I still really don't know the answer to that question.
The ancient dna we have for them so far is a set of not very resolved mtDna where some of the lineages were first claimed to have a correspondence to Anatolia/Turkey, but were later said to be so generic that they could have been in Italy since the Neolithic. As a set they most resembled a set from southern Germany (lots of "farmer" mtdna, but quite a bit of U5 too) which generally, I think, just means Late Neolithic/Early Bronze in areas with a lot of farmer impact but also some absorption of WHG/steppe.
The only other information is a non-published PCA of their autosomes where they look sort of Iberian, Tuscan/North Italian, Bulgarian? IF that's correct, and it's a big IF, then there sure wasn't any major replacement of the whole population in the first millennium BC by people from Anatolia. We know there were Bronze Age movements from Anatolia into Southeastern Europe, so I'm assuming into Italy as well, but whether there was specifically an Iron Age movement from Anatolia only into southern Toscana in the Iron Age, i.e. in the first millennium BC, that I don't know. If there was it was perhaps an elite movement? After all, look how similar Tuscans are to Albanians. Did the "Etruscans" from Anatolia go to Albania as well specifically in the first millennium BC? I think a lot of the analysis of the Tuscans in terms of the Etruscans was always done without placing Tuscany, and Italy as a whole, into the context of similar processes taking place in Greece and the more northern Balkans.
Anyway, as I said there are lots of threads on it, with this one being perhaps the most specific. Bottom line, I don't think modern dna is the way to go with this one.
http://www.eupedia.com/forum/thread...eory-on-the-Origi?highlight=Etruscans+Tuscans