Angela
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Given current conditions the answer is apparently yes.
The fact that astronaut Scott Kelly is an identical twin helped scientists in their analysis, but other changes were obvious, and some did not reverse completely with time.
"[h=2]Subtle changes[/h]One genetic change that did largely persist six months after Scott returned to Earth affected his chromosomes. Parts of them inverted, or flipped end-to-end. That leads to DNA damage and might be linked to the high amounts of radiation he experienced while in space.
Many of the caps at the ends of Scott’s chromosomes, called telomeres, also mysteriously lengthened during spaceflight, says Bailey. That’s the opposite of what she had expected, because telomeres shorten with age, and spaceflight stresses the body in much the same way as ageing does. Scott’s telomeres shortened within 48 hours of his return to Earth and are mostly back to their pre-flight lengths, although he does have more short telomeres now than before the flight. That could increase his risk of cardiovascular disease or certain types of cancer, Bailey says."
https://www.nature.com/articles/d41...witter&utm_campaign=NatureNews_&sf210906587=1
The fact that astronaut Scott Kelly is an identical twin helped scientists in their analysis, but other changes were obvious, and some did not reverse completely with time.
"[h=2]Subtle changes[/h]One genetic change that did largely persist six months after Scott returned to Earth affected his chromosomes. Parts of them inverted, or flipped end-to-end. That leads to DNA damage and might be linked to the high amounts of radiation he experienced while in space.
Many of the caps at the ends of Scott’s chromosomes, called telomeres, also mysteriously lengthened during spaceflight, says Bailey. That’s the opposite of what she had expected, because telomeres shorten with age, and spaceflight stresses the body in much the same way as ageing does. Scott’s telomeres shortened within 48 hours of his return to Earth and are mostly back to their pre-flight lengths, although he does have more short telomeres now than before the flight. That could increase his risk of cardiovascular disease or certain types of cancer, Bailey says."
https://www.nature.com/articles/d41...witter&utm_campaign=NatureNews_&sf210906587=1