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Genes and mutations associated with neuropsychological traits

If you tested your DNA with a personal genomics service like 23andMe, DeCODEme, FTDNA's Family Finder or another testing company, you can learn more about your risk factors for hundreds of diseases. Many of these SNP's are tested but not (yet) part of the report provided by personal genomics companies. This is free extra information.

We recommend that you install the SNPTips add-on for Mozilla Firefox to browse these pages. It allows you to upload your DNA results in the browser and show instantly which allele variant you have for each of the SNP listed below.

What can DNA tell you about yourself ?

List of genetically determined neuropsychological traits and their associated genes

Alleles : This list comprises positive, neutral and negative traits and conditions. Therefore we won't refer to risk factor like for diseases here. Correlated alleles can be either strongly associated (over 3x higher chances) or moderately associated (up to 3x higher chances) with each condition/trait.

In some cases the allele can be negatively correlated (lower chances). Depending on the testing company, sometimes A is reported as T, and G is reported as C, or vice-versa.

Testing companies :
A = 23andMe
(all versions) ; A2* = 23andMe (v2 only) ; A2 = 23andMe (v2 & v3) ; A3 = 23andMe (v3 only)
B = DeCODEme
C = Family Tree DNA Family Finder
Bold letters indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme.

Description Chromosome Gene SNP Alleles Tested by*
Emotional commitment 12 AVPR1A
Handedness B LRRTM1
B CTNNA2 rs1446109 AA, AG, GG A, C
rs1007371 AA, AT, TT A
rs723524 GG, GT, TT A, C
Happiness 17 SLC6A4 (SERT or 5HTT) rs25531 AA, AG, GG A3
rs2020933 AA, AT, TT A3
Hyperactivity 22 COMT rs6269 AA, AG, GG A
rs4633 CC, CT, TT A, C
rs4818 CC, CG, GG
rs4680 AA, AG, GG A, C
rs165599 AA, AG, GG A, C
Intelligence / IQ 5 ADRB2
7 CHRM2 rs324640 AA, AG, GG C
rs324650 AA, AT, TT A
rs2061174 AA, AG, GG A
rs2350780 AA, AG, GG A
rs6948054 AA, AG, GG A
rs7810473 AA, AG, GG A, C
rs1364402 CC, CT, TT A
rs1378646 CC, CT, TT A, C
rs7782965 CC, CT, TT A3
Intelligence / IQ (cognitive abilities, attention, memory) 6 DTNBP1 rs3213207 CC, CT, TT A
rs760761 AA, AG, GG A
rs1011313 AA, AG, GG A, C
rs2619522 AA, AC, CC A, C
rs2619528 AA, AG, GG A3
rs2619538 AA, AT, TT A
rs2619539 CC, CG, GG A3
11 BDNF rs6265 AA, AG, GG A
Intelligence / IQ (non-verbal) 20 SNAP25 rs363039 CC, CT, TT A, C
rs363043 CC, CT, TT A, C
rs353016 CC, CT, TT
rs363050 AA, AG, GG A
Intelligence (higher IQ if breastfed) 11 FADS2 rs1535 AA, AG, GG A
rs174575 CC, CG, GG A
Intelligence (learning from errors) 11 ANKK1 rs1800497 AA, AG, GG A
Intelligence (less cognitive decline with age) A DISC1 rs821616 AA, AT, TT A
10 SIRT1 rs3758391 CC, CT, TT A3, C
Memory 8 intergenic rs35753505 CC, CT, TT A, C
Memory (verbal) 6 TNF rs361525 AA, AG, GG A
Memory (long-term; logical) 22 PRNP rs1799990 AA, AG, GG A
Memory (episodic) A CAMTA1 rs4908449 CC, CT, TT A, C
3 CLSTN2 rs6439886 AA, AG, GG A, C
5 KIBRA rs17070145 CC, CT, TT A
Memory (traumatic) 22 COMT rs4680 AA, AG, GG A, C
Migratory behaviour 11 DRD4 VNTR 7-repeat
Novelty-seeking behaviour 11 DRD4 rs180095 CC, CT, TT
Optimism 17 SERT (5HTT) rs25531 AA, AG, GG A3
Pair-bonding (+ sociability) 3 OXTR rs7632287 AA, AG, GG A
rs75775 GG, GT, TT A, C
rs53576 AA, AG, GG A
rs2254298 AA, AG, GG A
rs237887 AA, AG, GG A, C
Ruthlessness 12 AVPR1A
Sexual desire 11 DRD4
Sleeping time (later) 4 CLOCK rs1801260 AA, AG, GG A, C

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