Directory Forum Gallery Facts & Trivia Genetics History Linguistics Friends Finder Europe Guide Belgium England France Germany Italy Netherlands Scotland Wales Eupedia Top > Europe Guide Top > Genetics > Health in your genes Genetically inherited traits, conditions and diseases What can DNA tell you about yourself ? Cardiovascular diseases Autoimmune diseases Other diseases Cancers Neuro-psychological conditions Physical & health-related traits Recommended reading on how genome-wide association studies are used to identify genetic variants associated with human diseases : Nature : Finding the missing heritability of complex diseases List of miscellaneous diseases with the associated genes => 36 other diseases and 151 SNP's listed. Risk alleles : Substantially lower risk (over 3x less), moderately lower risk (up to 3x less), normal, slightly higher risk (up to 3x more), greatly increased risk (over 3x more). Normal alleles marked with a * mean that the person is a carrier of the disease. Depending on the testing company, sometimes A is reported as T, and G is reported as C, or vice-versa. Testing companies : 1 = 23andMe ; 2 = DeCODEme Bold numbers indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme. However, as deCODEme tests almost twice more SNP's than 23andMe, most of the SNP's tested by 23andMe are also tested by deCODEme. Description Chromosome Gene SNP Risk alleles Tested by* Links   Acid reflux disease (GERD) 10 CYP2C19 Acid reflux disease (Eosinophilic esophagitis) 7 CCL26 rs2302009 AA, AC, CC 1 Acute intermittent porphyria 11 HMBS     mtDNA   Age-related Macular Degeneration 1 CFH rs800292 CC, CT, TT 1, 2 SNPedia rs3753394 CC, CT, TT 1, 2 rs1329428 AA, AG, GG 1, 2 rs1061147 AA, AC, CC 1, 2 rs1061170 CC, CT, TT 1   4 TLR3 rs3775291 AA, AG, GG 1     6 C2 rs547154 GG, GT, TT 1   10 HTRA1 rs11200638 AA, AG, GG 1       rs932275 AA, AG, GG 1, 2   10 ARMS2 rs10490924 GG, GT, TT 1       rs3750847 CC, CT, TT 1     19 C3 rs2230199 CC, CG, GG 1   Alzheimer's Disease 2 EIF2AK2 rs2254958 CC, CT, TT 1 SNPedia   3 MME rs1836915     6 TNF rs1799724 CC, CT, TT 1     9 DAPK1 rs4878104 1     rs4877365 1     9 GOLM1 rs10868366 GG, GT, TT     rs7019241 CC, CT, TT     9 intergenic rs9886784 AA, AC, CC     10 CALHM1 rs2986017 CC, CT, TT   10 PLAU rs2227564 1, 2 rs2227562 1, 2   11 GAB2 rs2373115 GG, GT, TT 1     11 BDNF rs6265 AA, AG, GG 1         rs11030104 1         rs2049045 1     11 SORL1 rs2070045 GG, GT, TT 1     rs661057 CC, CT, TT 1     rs668387 CC, CT, TT 1     rs689021 AA, AG, GG 1     rs641120 AA, AG, GG 1     rs12285364 CC, CT, TT 1     12 A2M rs669 AA, AG, GG 1     12 OLR1 rs1050283 CC, CT, TT     15 intergenic rs10519262 AA, AG, GG     17 MPO rs2333227 CC, CT, TT     rs12316150     19 APOE rs429358 CC, CT, TT   rs7412 1, 2 19 APOC1 rs4420638 AA, AG, GG 2   X PCDH11X rs5984894 AA, AG, GG 1   Alzheimer's Disease (early onset) 14 PSEN1     1 PSEN2     9 ABCA2 rs908832 AA, AG, GG 1     21 APP   Amyotrophic Lateral Sclerosis (ALS) 1 FLJ10986 rs6700125 CC, CT, TT 1 SNPedia   rs6690993 AA, AG, GG 1     rs10493256     rs6587852 1     rs1470407     rs333662     2 intergenic rs12473579 1     rs17027230 1     2 IL18RAP rs3771150 1     7 LOC653748 rs10260404 CC, CT, TT 1     7 DPP6 rs10239794 CC, CT, TT 1     7 PON2 rs12704795 1     7 MAGI2 rs757863 1     12 intergenic rs905080 1     12 intergenic rs1027615 1     15 LIPC rs3825776 TT, CT, CC 1     17 GRN rs9897526     rs34424835     rs850713     18 LOXHD1 rs988213 1     20 intergenic rs13036957 1     21 intergenic rs2836061 1   Creutzfeldt-Jakob Disease 11 CTSD rs17571 AA, AG, GG 1   20 PRNP rs1799990 AA, AG, GG 1   Cystic Fibrosis 7 CFTR i3000001 DD, DI*, II 1   Endometriosis 6 ESR1 rs9340799 AA, AG, GG 1   G6PD Deficiency X G6PD rs1050828 CC, CT, TT 1 Gallstones 8 ADRB3 rs4994 AA, AG, GG 1   Gestational Diabetes 10 TCF7L2 rs7903146 CC, CT, TT 1   Glaucoma 15 LOXL1 rs1048661 GG, GT, TT 1   rs3825942 CC, CT, TT 1       rs2165241 CC, CT, TT 1, 2         rs1078967 2   Glaucoma (open angle) 1 MYOC rs28936694 1   Gout 4 SLC2A9 rs1014290 AA, AG, GG 1       rs6449213 CC, CT, TT 1         rs737267 GG, GT, TT 1   Haemochromatosis 6 HFE rs1800562 AA, AG, GG 1, 2       rs1799945 CC, CG, GG 1, 2   Haemophilia X F8   X F9 Hearing loss (noise-induced) 6 HSP70-hom rs2227956 1   6 HSP70-1 rs1043618   6 HSP70-2 rs1061581 Hearing loss (age-related) 1 KCNQ4   8 GRHL2 Hearing loss (congenial) 13 GJB2 Link 1   5 TGBF1 Link 2 Hirschprung's disease 1 ECE1     2 SIP1     4 PHOX2B rs28939716 1     5 GDNF     10 RET rs3026785 1     rs17158558 1     rs1800858 1     rs2435357 1     13 EDNRB rs5352 1     19 NTN     20 EDN3 rs11570255 1         rs11570351 1     22 SOX10   Huntington's disease 4 HTT rs17781557   Intrahepatic Cholestasis of Pregnancy 2 ABCB11 rs2287622 AA, AG, GG 1     10 ABCC2 rs3740066 CC, CT, TT 1   Kidney Disease 15 MTHFS rs6495446 CC, CT, TT 1   6 PKHD1 rs28937907 1       rs28939099 1         rs28939383 1     16 UMOD rs28934584 1 Kidney stones (hypercalcaemia) 3 CASR Link 1 Non-alcoholic fatty liver disease 4 PPARGC1A rs2290602 GG, GT, TT   Nonsyndromic Deafness 1 KCNQ4 rs28937588 Link 1       rs28937589 1         rs28939710     4 WFS1 rs28937893     4 DSPP rs28929492     11 TECTA rs28939691       rs28939690     11 MYO7A rs28934903   13 GJB2 rs28931595   14 COCH rs28938175   16 CRYM rs28929490 Neurofibromatosis type II 22 NF2 Osteoarthritis 1 intergenic rs4140564 AA, AG, GG 1   2 FRZB rs7775 1     3 LOC344875 rs7639618 CC, CT, TT 1         rs9864422 CC, CT, TT         rs11718863 AA, AT, TT     20 GDF5 rs143383 CC, CT, TT 1 Osteoporosis 2 QPCT rs3770748 CC, CT, TT 1   11 LRP5 rs4988321 AA, AG, GG 1     rs3736228 CC, CT, TT 1     15 CYP19A1 rs17703883 1         rs16964201 1         rs12594287 1     20 BMP2 rs235754 1   Otitis 6 TNF rs1800750 AA, AG, GG 1     rs361525 AA, AG, GG 1     7 IL6 rs1800795 AA, AG, GG 1   Parkinson's Disease 12 LRRK2 rs34637584 AA, AG, GG 1 SNPedia       rs34778348 AA, AG, GG 1     1 USP24 rs287235 CC, CG, GG 1     2 USP40 rs838552 1     4 ADH1C rs283413 GG, GT, TT 1     4 SNCA rs356219 1   Placental Abruption 1 F5 rs6025 CC, CT, TT 1   Progressive Supranuclear Palsy 11 NR1H3 rs7120118 CC, CT, TT 1 Sarcoidosis 10 ANXA11 rs7091565     6 TNF rs1800629 AA, AG, GG 1   Sciatica 7 IL6 rs1800795 CC, CG, GG 1 SNPedia   rs1800796 CC, CG, GG 1     rs1800797 AA, AG, GG 1     rs13306435 AA, AT, TT   Sickle-cell Anemia 11 HBB i3003137 AA, AT*, TT 1 SNPedia Tourette's Syndrome 12 TPH2 rs4565946 CC, CT, TT 1   Uterine Fibroids 6 ESR1 rs9340799 AA, AG, GG 1   Wilson's disease 3 CP rs701753   13 ATP7B rs28942074 1         rs28942075 1     rs28942076 1 Site Sections Europe Directory Europe Forum Europe Photo Gallery Maps of Europe European Friend Finder Sitemap Travel Guides Europe Guide Belgium Guide England Guide France Guide Germany Guide Netherlands Guide Forum Sections European News EU politics & government European Economy Travelling in Europe European history European food Webmasters About Eupedia Advertising Contact Europe Banner Exchange Privacy Statement Terms of Use Copyright © 2004-2009 Eupedia All Rights Reserved About Eupedia - Privacy Statement - Terms of Use - Contact - Advertising - Sitemap