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Eupedia Top > Europe Guide Top > Health in your genes

Genetically inherited traits, conditions and diseases What can DNA tell you about yourself ? Diseases Neuro-psychological conditions Physical & health-related traits List of diseases with the associated genes => 76 diseases and 529 SNP's listed. Risk alleles : Substantially lower risk (over 3x less), moderately lower risk (up to 3x less), normal, slightly higher risk (up to 3x more), greatly increased risk (over 3x more). Normal alleles marked with a * mean that the person is a carrier of the disease. Depending on the testing company, sometimes A is reported as T, and G is reported as C, or vice-versa. Testing companies : 1 = 23andMe ; 2 = DeCODEme Bold numbers indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme. However, as deCODEme tests almost twice more SNP's than 23andMe, most of the SNP's tested by 23andMe are also tested by deCODEme. Description Chromosome Gene SNP Risk alleles Tested by* Links   Acid reflux disease (GERD) 10 CYP2C19 Acid reflux disease (Eosinophilic esophagitis) 7 CCL26 rs2302009 AA, AC, CC 1 Allergies (general) 1 FCER1A rs2427837 AA, AG, GG     rs2251746 CC, CT, TT 1   Abdominal Aortic Aneurysm 5 MTRR rs326118   7 IL6 rs1800796 CC, CG, GG 1     9 intergenic rs10116277 GG, GT, TT 1, 2   9 intergenic rs10757278 GG, GA, AA 1     9 intergenic rs10811661 1     14 MTHFD1 rs8003379 1 Intracranial Aneurysm 1 1p34-36   2 BOLL rs700651 AA, AG, GG 1   5 CSPG2 rs173686 CC, CT, TT 1     7 7q11   8 intergenic rs10958409 AA, AG, GG 1     9 intergenic rs10757278 GG, GA, AA 1     9 intergenic rs1333040 CC, CT, TT 1     9 9p21 rs10116277 1, 2     11 11q25   14 14q23–q31 rs767603 CC, CT, TT     19 19q13.1-13.3 Age-related Macular Degeneration 1 CFH rs800292 CC, CT, TT 1, 2 SNPedia rs3753394 CC, CT, TT 1, 2 rs1329428 AA, AG, GG 1, 2 rs1061147 AA, AC, CC 1, 2 rs1061170 CC, CT, TT 1   4 TLR3 rs3775291 AA, AG, GG 1     6 C2 rs547154 GG, GT, TT 1   10 HTRA1 rs11200638 AA, AG, GG 1       rs932275 AA, AG, GG 1, 2   10 ARMS2 rs10490924 GG, GT, TT 1       rs3750847 CC, CT, TT 1     19 C3 rs2230199 CC, CG, GG 1   Alzheimer's Disease 2 EIF2AK2 rs2254958 CC, CT, TT 1 SNPedia   3 MME rs1836915     6 TNF rs1799724 CC, CT, TT 1     9 DAPK1 rs4878104 1     rs4877365 1     9 GOLM1 rs10868366 GG, GT, TT     rs7019241 CC, CT, TT     9 intergenic rs9886784 AA, AC, CC     10 CALHM1 rs2986017 CC, CT, TT   10 PLAU rs2227564 1, 2 rs2227562 1, 2   11 GAB2 rs2373115 GG, GT, TT 1     11 BDNF rs6265 AA, AG, GG 1         rs11030104 1         rs2049045 1     11 SORL1 rs2070045 1     12 A2M rs669 AA, AG, GG 1     12 OLR1 rs1050283 CC, CT, TT     15 intergenic rs10519262 AA, AG, GG     17 MPO rs2333227 CC, CT, TT     rs12316150     19 APOE rs429358 CC, CT, TT   rs7412 1, 2 19 APOC1 rs4420638 AA, AG, GG 2 Alzheimer's Disease (early onset) 14 PSEN1     1 PSEN2     9 ABCA2 rs908832 AA, AG, GG 1     21 APP   Amyotrophic Lateral Sclerosis (ALS) 1 FLJ10986 rs6700125 CC, CT, TT 1 SNPedia   rs6690993 AA, AG, GG 1     rs10493256     rs6587852 1     rs1470407     rs333662     2 intergenic rs12473579 1     rs17027230 1     2 IL18RAP rs3771150 1     7 LOC653748 rs10260404 CC, CT, TT 1     7 DPP6 rs10239794 CC, CT, TT 1     7 PON2 rs12704795 1     7 MAGI2 rs757863 1     12 intergenic rs905080 1     12 intergenic rs1027615 1     15 LIPC rs3825776 TT, CT, CC 1     17 GRN rs9897526     rs34424835     rs850713     18 LOXHD1 rs988213 1     20 intergenic rs13036957 1     21 intergenic rs2836061 1   Ankylosing Spondylitis 5 ARTS-1 rs27044 CC, CG, GG 1   rs17482078 CC, CT, TT   rs10050860 CC, CT, TT 1   rs30187 CC, CT, TT 1   rs2287987 CC, CT, TT   1 IL23R rs11209026 AA, AG, GG 1   rs1004819 CC, CT, TT 1   rs10489629 AA, AG, GG 1   rs11465804 GG, GT, TT 1   rs1343151 CC, CT, TT 1   rs10889677 AA, AC, CC 1   5 LNPEP rs2303138 AA, AG, GG 1   6 - rs7743761 AA, AC, CC 1   12 CLSTN3 rs7302230 AA, AG, GG 1 Asthma 1 intergenic rs4950928 CC, CG, GG 1 6 PLA2G7 rs1805018 1, 2 rs1051931 1, 2   6 TNF rs1800629 AA, AG, GG 1   7 AAA1 rs324981 1   11 GSTP1 rs1695 AA, AG, GG 1, 2     17 GSDML rs7216389 CC, CT, TT 1, 2   Atrial Fibrillation 1 EDN2 rs5800 AA, AG, GG   4 AF (4q25) rs10033464 GG, GT, TT 1, 2   rs2200733 CC, CT, TT 1, 2 6 6q14-16 region 10 10q22 region Cancer (general risk) 3 FHIT     Link   6 E2F3   12 MDM2 rs2279744 GG, GT, TT 1     19 ZBTB7A   20 AURKA rs2273535 AA, AT, TT     Cancer (prevention) 2 CASP8 Cancer : Bladder 1 PTGS2 rs5275 CC, CT, TT 1   1 RUNX3 rs760805 AA, AT, TT   3 3q38 rs710521 AA, AG, GG 1   3 OGG1 rs1052133 CC, CG, GG   8 8q24 region rs9642880 GG, GT, TT 1, 2   Cancer : Brain 1 MTHFR rs1801131 GG, GT, TT 1   rs1801133 CC, CT, TT 1   Cancer : Breast 2 CASP8 rs17468277 1, 2       rs1045485 CC, CG, GG 1     2 intergenic rs13387042 AA, AG, GG 1, 2     4 intergenic rs2056116 AA, AG, GG     5 intergenic rs4700485 1, 2     5 MRPS30 rs4415084 2     5 intergenic rs889312 AA, AC, CC 1     6 TNF rs361525 AA, AG, GG 1     6 CDKN1A rs3176336 AA, AT, TT     7 XRCC2 rs3218536 AA, AG, GG 1     8 intergenic rs672888 1, 2     8 8q24 rs13281615 1     8 CYP51A1 rs1042638 1     9 intergenic rs3218005 AA, AG, GG     9 CDKN2A rs3731239 CC, CT, TT 1     10 FGFR2 rs1219648 AA, AG, GG 1     rs2981582 CC, CT, TT 1, 2     rs2420946 CC, CT, TT 1         rs2981582 CC, CT, TT 1     10 TCF7L2 rs12255372 GG, GT, TT 1     11 LSP1 rs3817198 CC, CT, TT 1, 2     11 ATM rs3218707 CC, CG, GG         rs4987945 CC, CG, GG         rs4986761 CC, CT, TT         rs3218695 AA, AC, CC         rs1800056 CC, CT, TT 1         rs1800057 CC, CG, GG         rs3092856 CC, CT, TT         rs1800058 CC, CT, TT 1         rs1801673 AA, AT, TT     12 CDKN1B rs34330 CC, CT, TT 1   13 BRCA2 rs1799954 CC, CT, TT 1 rs766173 GG, GT, TT 1 rs144848 GG, GT, TT 1 rs4987117 CC, CT, TT 1 rs1799954 CC, CT, TT 1 rs11571746 CC, CT, TT 1 rs11571747 AA, AC, CC rs4987047 AA, AT, TT 1 rs11571833 AA, AT, TT rs1801426 AA, AG, GG 16 16q12 region rs3803662 CC, CT, TT 1, 2 17 BRCA1 rs1799950 AA, AG, GG 1 rs4986850 AA, AG, GG 1 rs2227945 AA, AG, GG 1 rs16942 AA, AG, GG 1 rs1799966 AA, AG, GG 1   17 TP53 rs1042522 CC, CG, GG 1     19 CCNE1 rs997669 AA, AG, GG 1     20 AURKA rs2273535 AA, AT, TT     rs1047972 CC, CT, TT 1